Introduction: Research evidence indicates that maladaptive reorganization of the brain plays a critical role in amplifying pain experiences and pain chronification; there is, however, no clear evidence of change in brain wave activity among patients with chronic low back pain (CLBP). The objective of this study was to assess brain wave activity in patients with CLBP, compared to healthy control...

BACKGROUND The mouth is the most common site for measuring temperature. Oral mucositis may affect up to 40% of patients who receive chemotherapy. Thus far, mucositis has not been studied with regard to accurate thermometry. METHODS One hundred consecutive patients (25 per group) were self-referred on the basis of perception of mucositis, temperature measurement at home, or malaise or were ref...

INTRODUCTION No definitive data are available regarding the value of switching to an alternative TNF antagonist in rheumatoid arthritis patients who fail to respond to the first one. The aim of this study was to evaluate treatment response in a clinical setting based on HAQ improvement and EULAR response criteria in RA patients who were switched to a second or a third TNF antagonist due to fail...

The enzyme 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) catalyzes biosynthesis of progesterone (P) and all precursors of glucocorticoids, mineralocorticoids, androgens, and estrogens. Despite the broad interest raised by neurosteroids, the cellular localization of 3 beta-HSD has never been investigated in the brain. We took advantage of the availability of an antis...

The phylogenetic relationship among the kingdoms Animalia, Plantae, and Fungi remains uncertain, because of lack of solid fossil evidence. In spite of the extensive molecular phylogenetic analyses since the early report, this problem is a longstanding controversy; the proposed phylogenetic relationships differ for different authors, depending on the molecules and methods that they use. To settl...

In the present study, we investigated the effects of acute intracerebroventricular (icv) insulin administration on central mechanisms regulating urinary sodium excretion in simultaneously centrally NG-nitro-L-arginine methylester (L-NAME)-injected unanesthetized rats. Male Wistar-Hannover rats were randomly assigned to one of five groups: a) icv 0.15 M NaCl-injected rats (control, N = 10), b) i...

The haemodynamic effects of fazadinium were compared in two groups of elderly patients with class III functional heart failure about to undergo gastrointestinal surgery. Four patients were in sinus rhythm and four in atrial fibrillation. Following the assessment of baseline values fazadinium 1 mg kg-1 was injected i.v. and measurements obtained every 1 min for 15 min. In patients in sinus rhyth...

poverty is the most serious threat to natural resources and the environment and most of the poor are rural-based who engage in various agricultural activities. land is a critical asset for the rural poor and lacking means to appropriately intensify agriculture which compels the poor to either overuse or misuse this natural resource base to meet basic needs. this study presents empirical relatio...

as special depositional environments which are adjacent to the seas, deltas have provided a field for human habitat establishment. geomorphic features of deltas are in constant transformation due to their dynamic features. constructing dams on rivers can intensify these changes and cause either negative or positive consequences. minab delta in hormozgan province of iran is a round or crescent-s...

BACKGROUND Lack of a standardized and monitored technique to start rehabilitation of patients with acute coronary syndrome (ACS) in the coronary care unit. OBJECTIVE To describe the technique of and circulatory response to a 50-m walk (W50m). METHODS Experimental cross-sectional study of 65 patients with ACS; of these, 36 (54%) with acute myocardial infarction (AMI), Killip I, 29 (45.2%) wi...