(+)3H-3-PPP [(+)3H-3-(3-Hydroxyphenyl)-N-(1-propyl)-piperidine] binds with high affinity to brain membranes with a pharmacological profile consistent with that of sigma receptors. The distribution of (+)3H-3-PPP binding sites in brain and spinal cord of both guinea pig and rat has been determined by in vitro autoradiography with binding densities quantitated by computer-assisted densitometry. (...

Background:The utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (PPP). This effect is largely mediated by the increased or decreased concentration of platelets in the plasma. The current study aimed t...

Status of this Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Abstract The Point-to-Point Protocol (PPP) [1] provides a standard method for transporting multi-protocol datagrams over point-to-point links. This document describes how to build PPP sessions and encapsulate PPP packets ove...

Studies concerning the anatomical abnormalities of upper airways in patients affected by Obstructive Sleep Apnea Syndrome (OSAS) allowed the corrective surgical treatments in this syndrome. To provide an improvement or a definitive recovery of OSAS, various surgical treatments, i.e. functional nasal surgery, palatal surgery [Partial resection of palate (RPP), Uvulopalatopharingoplasty (UPPP), P...

Public-private partnership (PPP) is a form of co-operation of public and private sector, aiming at the realisation of public tasks connected to supplying public goods and services by private firms or with their participation. The significance and forms of PPP have been developing for several years according to changes in economic, social and political conditions of economic activity. At present...

Insulin-like growth factor 1 (IGF-1) plays a pleiotropic role in multiple myeloma (MM), that is, in survival, proliferation, chemotaxis, and angiogenesis. Strategies targeting the IGF-1 receptor (IGF-1R) may therefore be important to develop efficient anti-MM agents. In this work we investigated the effect of an IGF-1R tyrosine kinase (IGF-1RTK) inhibitor (picropodophyllin or PPP) in the 5T33MM...

BACKGROUND This retrospective analytic study was to evaluate diffusing capacity of the lung for carbon monoxide (DLCO) and predicted postoperative product (PPP) as predictors of postpneumonectomy cardiopulmonary complications. METHODS One-hundred fifty-one patients underwent pneumonectomy at Vancouver General Hospital from January 1992 to December 1997. The PPP was obtained by multiplying the...

OBJECTIVE Peak plantar pressures (PPPs) have been studied extensively as a contributing factor to skin breakdown, especially in the forefoot where most plantar neuropathic ulcers occur. The purposes of this article were to 1) describe an additional pressure variable, the peak pressure gradient (PPG), 2) determine whether the PPG is higher in the forefoot than in the rearfoot (even when compared...

An information retrieval performance measure that is interpreted as the percent of perfect performance (PPP) can be used to study the effects of the inclusion of specific document features or feature classes or techniques in an information retrieval system. Using this, one can measure the relative quality of a new ranking algorithm, the result of incorporating specific types of metadata or folk...