This work investigates the process of extraction of lemon balm (Melissa officinalis L.) by treatment with carbon dioxide at supercritical conditions. The process kinetics is studied at different operational conditions, and the influence of some important regime parameters (pressure, temperature particle size, solvent flow-rate) on the extraction yield is experimentally determined. Besides the i...

Speciation is an important evolutionary process that occurs when barriers to gene flow evolve between previously panmictic populations. Although individual barriers to gene flow have been studied extensively, we know relatively little regarding the number of barriers that isolate species or whether these barriers are polymorphic within species. Herein, we use a series of field and lab experimen...

1. Patient Engagement and the PCMH: A Pilot Survey in Four Clinical Settings Carole Upshur UMMS/DFMCH; Lee Hargraves, DFMCH; Achankeng Afiadata, Azra Borogovac, Julianna Clough, Jonathan Eisenberg, Josephine Harrington, Cailtin Lawrence, John Madore, Navine Nasser-Ghodsi, Jennifer Perez, Melissa Pergakis, Andrew Piper, Matthew Sloan, and Karen Tanner (Clinical/Translational Research Pathway stu...

OBJECTIVE Melissa officinalis (lemon balm) is contemporaneously used as a mild sedative and/or calming agent. Although recent research has demonstrated modulation of mood in keeping with these roles, no studies to date have directly investigated the effects of this herbal medication on laboratory-induced psychological stress. METHODS In this double-blind, placebo-controlled, randomized, balan...

1 Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Afyon Kocatepe University, Afyonkarahisar, TURKEY 2 Faculty of Medicine, Department of Pharmacology, Afyon Kocatepe University, Afyonkarahisar, TURKEY 3 Faculty of Veterinary Medicine, Department of Internal Medicine, Afyon Kocatepe University, Afyonkarahisar, TURKEY 4 Faculty of Art and Science, Department of Chemistr...