The B vitamins are components of one-carbon metabolism (OCM) that contribute to DNA synthesis and methylation. Homocysteine, a by-product of OCM, has been associated with coronary heart disease, stroke and neurological disease. To investigate genetic factors that affect circulating vitamin B6, vitamin B12, folate and homocysteine, a genome-wide association analysis was conducted in the InCHIANT...

We used Optical Coherence Microscopy (OCM) to monitor structural and functional changes due to ischemic stroke in small animals brains in vivo. To obtain lateral resolution of 2.2 μm over the range of 600 μm we used extended focus configuration of OCM instrument involving Bessel beam. It provided access to detailed 3D information about the changes in brain vascular system up to the level of cap...

Quantum lithography (QL) has been suggested as a means of achieving enhanced spatial resolution for optical imaging, but its realization has been held back by the low multiphoton detection rates of recording materials. Recently, an optical centroid measurement (OCM) procedure was proposed as a way to obtain spatial resolution enhancement identical to that of QL but with higher detection efficie...

There is a growing debate among developmental theorists concerning the perception of causality in young infants. Some theorists advocate a top-down view, e.g., that infants reason about causal events on the basis of intuitive physical principles. Others argue instead for a bottom-up view of infant causal knowledge, in which causal perception emerges from a simple set of associative learning rul...

Tissue engineered medical products (TEMPs) are often three-dimensional (3D) hybrid materials consisting of a porous scaffold upon which the tissue is grown. However, monitoring of the developing tissue deep within the scaffold is hampered by its turbidity. We have sought new ways to probe the interior of the scaffold with the same resolution as conventional laser scanning confocal microscopy bu...

The oxygen-free conversion of methane on transition-metal catalysts could be an interesting alternative to the oxygen-containing conversion (OCM) due to its higher selectivity towards higher hydrocarbons (C2+). So far, the main obstacle has been the low conversion rate compared to the OCM process. This is mostly ascribed to the fact that oxygen-free CH4-conversion is accompanied by a quick depo...

The benzophenanthridine alkaloids sanguinarine, chelerythrine and chelidonine were reported previously to provoke cell death in a variety of tumor cells suggesting their potential application as anticancer agents. Here we tested their effects on a primary human uveal melanoma cell line, OCM-1. Flow cytometric analysis of annexin V binding/PI exclusion and DNA fragmentation disclosed that all th...

In this study, we aimed to enhance the catalytic activity of perovskite catalysts and elucidate their behavior in oxidative coupling methane (OCM), using alkali-added LaAlO3 catalysts. We prepared LaAlO3_XY (X = Li, Na, K, Y mol %) applied them OCM reaction. The results showed that catalysts’ activities were promoted compared catalyst. reaction, ethane was first synthesized through dimerization...

The performance of the Mn-Na2WO4/SiO2 catalyst for oxidative coupling methane (OCM) has been ascribed to crystalline phases that are not present at reaction temperatures (>700 °C). evolution W and Mn sites structure was monitored via in situ TPO-XRD, -Raman, -XANES spectroscopies. TPO-XRD shows identified on Mn-Na2WO4/SiO2, Na2WO4/SiO2, WO3/SiO2 catalysts room temperature do exist relevant OCM ...