نتایج جستجو برای: انکس 13
تعداد نتایج: 332548 فیلتر نتایج به سال:
Interleukin (IL)-13 mediates its activities via a complex receptor system. Interleukin-13 receptor -1 chain (IL-13R 1) binds IL-13 with low affinity, but does not signal. However, when IL-13R 1 combines with IL-4 receptor (IL-4R ), a signaling high affinity receptor complex for IL-13 is generated. In contrast, IL-13R 2 alone binds IL-13 with high affinity, but does not signal and has been postu...
در تاریخچه انقلاب اسلامی، لحظاتی وجود دارد که به‌صورت دال‌های متعدد گفتمان انقلاب درآمده‌اند و انقلاب را می‌توان با آنها فهم و درک کرد. 13 آبان، یکی از مهم‌ترین این لحظات است. این پژوهش با رویکرد کیفی به رفتارشناسی مشارکت‌کنندگان در راهپیمایی 13 آبان 1395 در شهر تهران می‌پردازد. بررسی کارکردهای راهپیمایی 13 آبان از دیدگاه مشارکت‌کنندگان، انگیزه آنها و نیز ویژگی‌های آنها، اهداف اصلی پژوهش را ت...
چکید ه سابقه و هدف فاکتور13 انعقادی، آخرین آنزیم آبشار انعقادی است و ژن زیر واحد A روی کروموزم شش قرار گرفته است. کمبود ارثی فاکتور 13، در حدود 2000000/1 نفر جمعیت رخ می‌دهد. این تحقیق با هدف شناسایی جهش‌ها در ژن زیر واحد A بیماران و روش غربالگری مناسب ناقلین انجام گرفت. مواد و روش‌ها در یک مطالعه کاربردی، پس از تکمیل فرم رضایت‌نامه، نمونه خون از 21 بیمار مبتلا به کمبود فاکتور 13 و خا...
These lecture notes present some basic intuitions underlying structural equations modeling (SEM). If you find this technique useful in your research, I suggest that you take a semester-long course on SEM and/or hierarchical linear model (HLM). It turns out that SEM and HLM are essentially the same technique but some things are easier to implement in one versus the other so disciplines tend to f...
8Love never fails; but if there are gifts of prophecy, they will be done away; if there are tongues, they will cease; if there is knowledge, it will be done away. 9For we know in part and we prophesy in part; 10but when the perfect comes, the partial will be done away. 11When I was a child, I used to speak as a child, think as a child, reason as a child; when I became a man, I did away with chi...
The role of the endogenous apelin system in pregnancy is not well understood. Apelin's actions in pregnancy are further complicated by the expression of multiple forms of the peptide. Using radioimmunoassay (RIA) alone, we established the expression of apelin content in the chorionic villi of preeclamptic (PRE) and normal pregnant women (NORM) at 36-38 wk of gestation. Total apelin content was ...
IL-13 and IL-4 are key contributors to the asthmatic phenotype. The temporal role of these cytokines in airway function, inflammation, and remodeling were assessed in a chronic murine model of Asperigillus fumigatus-induced allergic asthma. IL-13 and IL-4 protein levels were significantly elevated by 30 days after conidia challenge in A. fumigatus-sensitized mice. Furthermore, IL-13Ralpha1 mRNA...
PURPOSE Interleukin (IL)-13, a Th2-type cytokine, plays a pivotal role in the pathogenesis of asthma through its direct effects on airway smooth muscles. A naturally occurring IL-13 polymorphism, R110Q, is strongly associated with increased total serum IgE levels and asthma. In the present study, we aimed to determine whether the IL-13 R110Q variant would display different biochemical propertie...
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