The early genes E6 and E7 of human papillomavirus type 16 (HPV16) are consistently and exclusively expressed in HPV16-induced cancer lesions and play major roles in the development and maintenance of the malignant phenotype. Because this protein is a good example of a tumor-associated antigen, we have used E7 as a model antigen to test the potential of an experimental vaccine as an immunotherap...

The success of a new technology implementation effort is ultimately dependent upon both management and user support for the project. While recent literature is replete with instances in which measures of support have been correlated with measures of success, potential objective analysis has not been well examined. Furthermore, although these effects may be inherently specific to a given organiz...

One of the most important tasks during development of hardware/software systems for assisted and automatic driving is determination of vehicle position with sufficient accuracy in real time. Most of experimental systems developed yet are based on relatively expensive Real Time Kinematic technique which primary usage is land and hydrographical surveys with centimetre level accuracy. The paper is...

In the next few years, surveyors using high productivity, real-time kinematic (RTK) positioning and indeed all other precision positioning users will be faced with a barrage of new global navigation satellite system (GNSS) signals from GPS, GLONASS, GALILEO and possibly COMPASS/Beidou2 as well as Satellite Based Augmentation Systems (SBAS) signals and Regional Navigation Satellite Systems (RNSS...

Service oriented technologies allow Service Based Applications (SBAs) to be easily built by composing independent services available in a network and provided by many actors under conditions that may change in time. Therefore services need to be dynamically selected and composed when an SBA is required along with parameters representing the service delivery conditions. In this paper we propose ...

In this work, we identified activities relevant to the adaptation of Service Based Applications (SBAs) from existing service engineering approaches as well as activities relevant to the software maintenance process. We then mapped these two sets of activities to a reference life-cycle model from a Large European project. The results highlight the software maintenance techniques that can be reus...

Surface deformation data can be used to provide early warnings of geohazards and are useful in a variety research fields. The Small BAseline Subset InSAR (SBAS-InSAR) boosts the sampling rate improves accuracy extraction by restricting temporal spatial baselines. However, various factors, such as types ground objects seasons, affect coherence between SAR images. Traditional SBAS-InSAR employs f...

The L1-only Satellite-Based Augmentation System (SBAS) Minimum Operational Performance Standards (MOPS) were developed long before any SBASs were certified for operation. During the development and certification of the Wide Area Augmentation System (WAAS), it was discovered that the zero-mean Gaussian basis of the Vertical Protection Level (VPL) equation was not strictly true for some error sou...

Safety-of-life GNSS augmentation systems must provide bounds on the probability with which hazardous navigation errors occur. This paper develops conservative bounding methods both for space-based augmentation systems (SBAS) and for ground-based augmentation systems (GBAS) by using excess-mass functions. The excess-mass concept, which employs conservative bounding functions with integrated dens...

Methods Qualitative research was considered most appropriate to understand the attitudes and beliefs of rural women. Semi-structured, one to one interviews were conducted on 12 participants; 4 pregnant women/delivered within 1 year, 4 SBAs and 4 FCHVs/TBAs to gauge a variety of opinions. A purposive approach was used as well as convenience sampling and snowball sampling from the district hospit...