Laparoscopic surgery has been widely accepted as a feasible and safe treatment modality in many cancers of the gastrointestinal tract. However, most guidelines on gallbladder cancer (GBC) regard laparoscopic surgery as a contraindication, even for early GBC. This study aims to evaluate and compare recent surgical outcomes of laparoscopic and open surgery for T1(a,b) GBC and to determine the opt...

Using speech data, it is difficult to learn through machine learning how diagnose Parkinson's disease (PD) and evaluate the effects of treatment. For this issue, article has developed a three-stage PD discovery method. The base classifiers used in initial stage are logistic regression (LR), K-nearest neighbor (KNN), naive bayes (NB), support vector (SVC), decision tree (DT). second stage, or st...

Abstract Groundwater availability is one of the key anxieties in most semi-arid regions Ethiopia. The purpose this study was to investigate groundwater potential zone map alluvial plain Gambela. applied analytic hierarchy process (AHP) models with four different machine learning algorithms: random forest classifier (RFC), gradient boosting (GBC), decision tree (DTC), and K-neighbor (KNC). featu...

For the problems of inaccurate recognition and high missed detection rate existing mask algorithms in actual scenes, a novel algorithm based on YOLO-GBC network is proposed. Specifically, backbone part, global attention mechanism (GAM) integrated to improve ability extract key information through cross-latitude interaction. The cross-layer cascade method adopted feature pyramid structure achiev...

AIM To investigate the prognostic value of the combination of preoperative plasma fibrinogen and CA199 in patients with gallbladder carcinoma (GbC). METHODS The clinicopathological data of 154 GbC patients were retrospectively reviewed after surgery. A receiver 1451 April 7, 2018|Volume 24|Issue 13| WJG|www.wjgnet.com ORIGINAL ARTICLE Prognostic significance of combined preoperative fibrinogen ...

The prognosis of advanced gall bladder carcinoma (GBC) remains poor despite the addition newer targeted therapies. HER2 is a potential therapeutic target expressed in up to 20% GBC. We present an analysis or metastatic HER2-amplified overexpressed GBC treated with trastuzumab and chemotherapy from Indian cancer center. Patients immunohistochemical evidence overexpression (IHC 3+) amplification ...

Purpose: Xanthogranulomatous cholecystitis (XGC) is an uncommon, benign destructive and chronic inflammatory disease which is characterized by a marked proliferative fibrosis within the gallbladder wall. XGC occasionally involves adjacent organs and mimicking an advanced gallbladder carcinoma (GBC). The purpose of this study was to review the clinical manifestations, radiologic and pathologic f...

Gallbladder cancer (GBC) is one of the most unfavorable prognostic tumor, and immediate growth and distant metastasis are important factors associated with the poor prognosis of patients with this disease. Standard and variant isoforms of CD44 are associated with tumor growth, metastasis, and epithelial-mesenchymal transition (EMT), although their roles in GBC are unclear. We investigated the r...

With ready availability of abdominal ultrasound, asymptomatic gallstones (AsGS) are being diagnosed with increasing frequency. Management decisions need to take into account the natural history of AsGS as well as the risks of cholecystectomy. Long-term follow up studies from the West have consistently shown that only a small minority of asymptomatic gallstones lead to development of symptoms or...

Gallbladder cancer (GBC) is a rare but highly aggressive cancer for which no well-accepted prognostic biomarkers have been identified. Thymus cell antigen 1 (Thy1), also known as cluster of differentiation (CD)90, and integrin α6 (ITGA6), also known as CD49f, are important molecules in cancer and putative markers of various stem cell types. However, their role in GBC remains to be elucidated. I...