Epithelial ovarian serous cancer arising in endometrioma is an uncommon phenomenon. Here, we present a case of postmenopausal high-grade carcinoma associated with endometrioma. A 64-year-old woman attended the clinic pelvic pain and persistent vaginal discharge. Ultrasonography revealed endometrial thickness 37*23 mm left cystic adnexal mass. During operation, solid mass grossly located cul-de-...

The effect of c10fazimine and 6 analogues (B 369 1 , B 3 7 1 3 , B 3640, B 3648, B 720 and B 749) on the viabi l i ty of Mycobacterium /eprae was tested i n a rapid, radiometric, ill vitro assay. Thi rteen human and I armadi l lo-derived freshly-extracted M. /eprae, maintained in peritoneal macro phages, incorporated 3H -thymidine to significant levels as compared to paral lel cu l tures with h...

Sensitive to apoptosis gene (SAG), also known as RBX2, ROC2, or RNF7, is a RING component of SCF E3 ubiquitin ligases, which regulates cellular functions through ubiquitylation and degradation of many protein substrates. Although our previous studies showed that SAG is transcriptionally induced by redox, mitogen and hypoxia via AP-1 and HIF-1, it is completely unknown whether and how SAG is ubi...

Sex-determination in Caenorhabditis elegans requires regulation of gene transcription and protein activity and stability. sel-10 encodes a WD40-repeat-containing F-box protein that likely mediates the ubiquitin-mediated degradation of important sex-determination factors. Loss of sel-10 results in a mild masculinization of hermaphrodites, whereas dominant alleles of sel-10, such as sel-10(n1074)...

An important aspect of the hunting strategy of neotropical social wasps (I-Iymenoplera: Vespidae) is where thcy hunt. Three species used two behavioural components in their se lection ofa place 10 search for prey. The wasps utili zed lhe odom of (j'eshly damaged leaves as cues (which could be synomones) to se lecl which leaves to inspect and also they remembered a place to which they were stron...

The copper (II) complexes (CuL(2)) were prepared by reaction of Cu(CH(3)COO)(2) with the corresponding derivatives of acylthioureas in a Cu:HL molar ratio of 1:2. Acylthiourea ligands, N,N-diethyl-N'-(R-benzoyl) thiourea (HL(1-3)) [R=H, o-Cl and p-NO(2)] were synthesized in high yield (78-83%) and characterized by elemental analysis, infrared spectroscopy, (1)H and (13)C NMR spectroscopy. The c...