MiR-206 acts as a potential tumor suppressor during carcinogenesis and a regulatory factor in osteoblasts differentiation, but its modulatory mechanism remains unclear. In this study, we used a quantitative proteomics method, difference gel electrophoresis (DIGE), to profile the protein variation in A549 lung cancer cells with and without miR- 206 transfection. We identified a total of 17 diffe...

MicroRNAs (miRNAs) are thought to have an important role in tumor metastasis by regulating diverse cellular pathways. Here, we describe the function and regulation network of miR-206 in gastric cancer (GC) metastasis. MiR-206 expression was downregulated in GC cells especially in high metastatic potential cells and was also significantly decreased in metastatic lesions compared with their corre...

in this paper cufe2o4, nanocrystalline powders were prepared. also, the supported cu ferrite was obtained by impregnation of the supports with cu and fe nitrates solutions, for calcination temperature 450 ºc. the samples were characterized by x-ray powder diffraction (xrd) and fourier transform-infrared spectroscopy (ft-ir). photocatalytic degradation of acid red 206 in water was studied. cufe2...

هدفت هذه الد ا رسة التعرف إلى العلاقة المتبادلة بين الشخصية الحدية–والتي تتميز بعدم الاستق رر في العلاقات الأشخاص وفي الصورة الذاتية، والأمزجة، والتحكّم بالاندفاعات–والجهد العاطفي والشعور بالفخر للانتماء الجامعة لدى طلبة جامعة القدس المفتوحة فرع طولكرم. واعتمدت المنهج الوصفي الارتباطي التحليلي وطبقت ثلاثة مقاييس لقياس متغي رت على عينة مكونة من) 334 (طالبًا وطالبة من أظهرت النتائج أن تقدي أف رد لا...

Twist-1 is mostly expressed during development and has been previously shown to control myogenesis. Because its regulation in muscle has not been fully exploited, the aim of this project was to identify micro (mi)RNAs in muscle that regulate Twist-1. miR-206, one of the most important muscle-specific miRNAs (myomiRs), was identified as a possible regulator of Twist-1 mRNA. Luciferase assays and...

Mutations in the gene encoding glutamine-fructose-6-phosphate transaminase 1 (GFPT1) cause the neuromuscular disorder limb-girdle congenital myasthenic syndrome (LG-CMS). One recurrent GFPT1 mutation detected in LG-CMS patients is a c.*22C>A transversion in the 3'-untranslated region (UTR). Because this variant does not alter the GFPT1 open reading frame, its pathogenic relevance has not yet be...