Alcaligenes eutrophus A5 catabolizes biphenyl to CO2 via benzoate and 4-chlorobiphenyl to 4-chlorobenzoate. In curing and conjugation experiments, the A5 endogenous 51-kb IncP1 plasmid pSS50 was found to be dispensable for biphenyl and 4-chlorobiphenyl catabolism. Transfer of the biphenyl- and 4-chlorobiphenyl-degrading phenotype by means of pSS50 was observed at a frequency of 10(-5) per trans...

During the process of normal hematopoiesis, proliferation is tightly linked to maturation. The molecular mechanisms that lead to production of mature effector cells with a variety of phenotypes and functions from a single multipotent progenitor are only beginning to be elucidated. It is important to determine how these maturation events are regulated at the molecular level, because this will pr...

argumentation frameworks [Dun95] take a very simple view on argumentation as they do not presuppose any internal structure of an argument. Abstract argumentation frameworks only consider the interactions of arguments by means of an attack relation between arguments. Definition 1 (Abstract Argumentation Framework). An abstract argumentation framework AF is a tuple AF = (Arg,→) where Arg is a set...

OBJECTIVE Combined hyperlipidemia is a common disorder, characterized by a highly atherogenic lipoprotein profile and a substantially increased risk of coronary heart disease. The purpose of this study was to establish whether variations of apolipoprotein A5 (APOA5), a newly discovered gene of lipid metabolism located 30 kbp downstream of the APOA1/C3/A4 gene cluster, contributes to the transmi...

During cerebral cortex development, post-mitotic neurons interact with radial glial fibers and the extracellular environment to migrate away from the ventricular region and form a correct laminar structure. Integrin receptors are major mediators of cell–cell and cell– extracellular matrix interactions. Several integrin heterodimers are present during formation of the cortical layers. The a5b1 r...

APOBEC3 proteins inhibit HIV-1 replication in experimental systems and induce hypermutation in infected patients; however, the relative contributions of several APOBEC3 proteins to restriction of HIV-1 replication in the absence of the viral Vif protein in human primary CD4(+) T cells and macrophages are unknown. We observed significant inhibition of HIV-1Δvif produced in 293T cells in the pres...

Cryptanalysis is the process of finding flaws or oversights in an encryption algorithm. Nearly, all algorithms are carefully examined through cryptanalysis to determine security system which algorithm has been employed. A5/1 a well-known inbuilt mobile phone for securing GSM communication, and therefore, this also important. consists three linear feedback registers lengths 23, 22, 19 bits. Due ...

argumentation frameworks [Dun95] take a very simple view on argumentation as they do not presuppose any internal structure of an argument. Abstract argumentation frameworks only consider the interactions of arguments by means of an attack relation between arguments. Definition 1 (Abstract Argumentation Framework). An abstract argumentation framework AF is a tuple AF = (Arg,→) where Arg is a set...

The ability of platelets to provide a highly reactive surface for the recruitment of other platelets and leukocytes to sites of vascular injury is critical for hemostasis, atherothrombosis, and a variety of inflammatory diseases. The mechanisms coordinating platelet-platelet and plateletleukocyte interactions have been well defined and, in general, it is assumed that increased platelet activati...