Herein we describe NMR experiments and structural modifications of 4-methyl-2-phenylpyrimidine-N-acylhydrazone compounds (aryl-NAH) in order to discover if duplication of some signals in their ¹H- and ¹³C-NMR spectra was related to a mixture of imine double bond stereoisomers (E/Z) or CO-NH bond conformers (syn and anti-periplanar). NMR data from NOEdiff, 2D-NOESY and ¹H-NMR spectra at differen...

Boron-10 enriched boric acid, H3B03, was converted to the corresponding sodium borohydride, NaBH4, in essentially quantitative yields, by using slightly modified literature methods involving the formation of butyl borate, (n-OBu)jB, first and then reacting it with NaH in mineral oil. The oxidation reaction of NaBH« with I2 in diglyme and subsequent addition/purification in dioxane gave Na[B3Hg]...

The sequence specificity of hammerhead ribozyme cleavage has been re-evaluated with respect to the NUH rule. Contrary to previous reports it was found that substrates with GAC triplets were also cleaved. This was established in three different sequence contexts. The rate of cleavage under single turnover conditions was between 3 and 7% that of cleavage 3' of GUC. Specificity of cleavage of subs...

Ein Geologe steht in einem unbekannten Höhlensystem. Er startet vier Drohnen, die sich selbstständig ihren Weg suchen. Die zurückgelegte Strecke wird in Echtzeit kartografiert und als dreidimensionales Modell im Hauptquartier angezeigt. Die beschriebene Szene stammt aus dem Film ” Prometheus Dunkle Zeichen“ aus dem Jahr 2012 und gab die Motivation für das hier vorgestellten Framework. Es sollte...

transistors as a function of body thickness Kuniharu Takei, Steven Chuang, Hui Fang, Rehan Kapadia, Chin-Hung Liu, Junghyo Nah, Ha Sul Kim, E. Plis, Sanjay Krishna, Yu-Lun Chueh, and Ali Javey Electrical Engineering and Computer Sciences, University of California, Berkeley, California 94720, USA Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA ...

Reaction of 1-(3-cyanopropoxy)-3,4-dihydronaphthalene-2-carbonitriles with potassium tert-butoxide gave 5-amino-1,2,6,7-tetrahydrobenzo[f]furo[2,3-c]isoquinolines via a Truce-Smiles rearrangement. The 5-amino group was transformed to the bromo derivatives which were allowed to react with aliphatic cyclic amines to produce amino derivatives. In contrast, a combination of imidazole and NaH gave a...