Reports show that, while the mechanism remains unknown, salvianolate lyophilized injection (SLI) improves functional recovery after stroke in diabetic rats. In this study, we investigated the mechanism and effect of SLI on stroke outcome in type 1 diabetic (T1DM) rats. T1DM were induced in adult male Wistar rats by injecting streptozotocin. T1DM rats were then subjected to 90 minutes of middle ...

Children with specific language impairment (SLI) have distinctive impairments in the comprehension of sentences that involve long-distance syntactic relationships. This has been interpreted as evidence for impairment in an innate grammatical module. An alternative theory attributes such difficulties to lower level problems with speech perception or deficits in phonological working memory. These...

Within the domain-general theory of language impairment, this study examined body posture and hand movement imitation in children with specific language impairment (SLI) and in their age-matched peers. Participants included 40 children with SLI (5 years 3 months to 6 years 10 months of age) and 40 children with typical language development (5 years 3 months to 6 years 7 months of age). Five tes...

PURPOSE To explore the sensitivity of children with specific language impairment (SLI) to amplitude-modulated and durational cues that are important for perceiving suprasegmental speech rhythm and stress patterns. METHOD Sixty-three children between 7 and 11 years of age were tested, 21 of whom had a diagnosis of SLI, 21 of whom were matched for chronological age to the SLI sample, and 21 of ...

BACKGROUND Although it is widely recognized that substantial heterogeneity exists in the cognitive profiles of children with Developmental Coordination Disorder (DCD), very little is known about the language skills of this group. AIMS To compare the language abilities of children with DCD with a group whose language impairment has been well described: children with Specific Language Impairmen...

BACKGROUND Considerable evidence suggests that performance across a variety of cognitive tasks is effectively supported by the use of verbal and nonverbal strategies. Studies exploring the usefulness of such strategies in children with specific language impairment (SLI) are scarce and report inconsistent findings. AIMS To examine the effects of induced labelling and auditory cues on the perfo...

Children with specific language impairments (SLIs) show impaired perception and production of spoken language, and can also present with motor, auditory, and phonological difficulties. Recent auditory studies have shown impaired sensitivity to amplitude rise time (ART) in children with SLIs, along with non-speech rhythmic timing difficulties. Linguistically, these perceptual impairments should ...

PURPOSE This study examined the perception of fundamental frequency (f0) patterns by Cantonese children with and without specific language impairment (SLI). METHOD Participants were 14 five-year-old children with SLI, and 14 age-matched (AM) and 13 four-year-old vocabulary-matched (VM) controls. The children identified a word from familiar word pairs that illustrated the 8 minimally contrasti...

Fifty-seven children (ages in years;months: 5;7-8;8) with and without Specific Language Impairment (SLI) participated in judgment and elicitation tasks designed to evaluate their understanding of restrictions associated with irregular verb forms. The performance of the SLI group was similar to the performances of the control groups in that all children demonstrated high levels of sensitivity to...

The aim of the present study is to investigate the relationship between language comprehension and language production in Swedish children. This was done longitudinally with 10 children with specific language impairment (SLI), aged 4;0 to 6;3 at Time I, and 10 children with unimpaired language development, aged 3;1 to 3;7 at Time I. The target structure was subordination, more precisely relativ...