In cognitive radio, spectrum sensing is a challenging task. In this letter, a new spectrum sensing method is proposed based on Goodness of Fit test (GoF) of the energy of the received samples with a chi-square distribution. We derive the test statistic and evaluate the performance of the proposed method by Monte Carlo simulations. It is shown that our proposed spectrum sensing method outperform...

Over the past decade, there has been a lot of interest towards aspect-oriented programming (AOP). Hannemann and Kiczales developed AspectJ implementations of the Gang-of-Four (GoF) design patterns. Their study was continued by Hachani, Bardou, Borella, and others. However, no one has tried to improve the implementations by using generics or reflective programming. This research faces up to this...

Since its introduction in computer science, the concept of pattern has flourished. Several conferences and workshops focus on writing and disseminating patterns. Consequently, a large number of patterns exist and it is sometimes difficult to find the right patterns and to choose among many candidate, when solving a given problem. In this paper, we introduce a simple recommender system to help u...

The Na+ leak channel (NALCN) is highly expressed in the brain, where it mediates a persistent current that contributes to resting membrane potential (RMP) of neurons. This regulates neuronal excitability underlying processes, such as locomotion and circadian rhythm. Recently, we have shown, co-expression UNC80, UNC79 FAM155A required form functional NALCN complex heterologous systems. To date, ...

Proprotein Convertase Subtilisin Kexin type 9 (PCSK9), comprises 12 exons, encoded for an enzyme which plays a critical role in the regulation of circulating low density lipoprotein. The gain-of-function (GOF) mutations aggravate degradation LDL receptors, resulting familial hypercholesterolemia (FH), while loss-of-function (LOF) lead to higher levels lower cholesterol, and preventing from card...

Abstract Hereditary a-tryptasemia (HaT) is a genetic trait defined by elevated serum tryptase caused increased TPSAB1 copy number and associated with multiple phenotypes including pain. CACNA1H encoding the voltage-gated calcium channel Ca V3.2 overlaps locus where partial gain-of-function (GOF) haplotype containing 3 linked variants has been shown to be co-inherited HaT in ~2/3 of individuals....