Oxidative damage to membrane lipid is one of the prime events occurring in aging and other undesirable physiological processes. In this study experiments were performed on liposomes (prepared either from crude erythrocyte phospholipids or purified egg yolk phosphatidylcholine) as models of lipid bilayer portion of biomembranes. The effects of β-carotene, and phospholipid composition on peroxida...

The biosynthesis pathway to diadinoxanthin and fucoxanthin was elucidated in Phaeodactylum tricornutum by a combined approach involving metabolite analysis identification of gene function. For the initial steps leading to β-carotene, putative genes were selected from the genomic database and the function of several of them identified by genetic pathway complementation in Escherichia coli. They ...

Carotenoids are natural fat-soluble pigments that provide bright coloration to plants and animals. Dietary intake of carotenoids is inversely associated with the risk of a variety of cancers in different tissues. Preclinical studies have shown that some carotenoids have potent antitumor effects both in vitro and in vivo, suggesting potential preventive and/or therapeutic roles for the compounds...

Lycopene β-cyclase (LYCB) is the key enzyme for the synthesis of β-carotene, a valuable component of the human diet. In this study, tomato constitutively express Lycb-1 was engineered. The β-carotene level of transformant increased 4.1 fold, and the total carotenoid content increased by 30% in the fruits. In the transgenic line, the downstream α-branch metabolic fluxes were repressed during the...

The color is a sensory attribute that influence decisively the judgment of consumers in certain type of food and therefore, the food industries have added dyes to their products. Natural dyes have been demanded by consumers but there are some limitations in its use such as low water solubility and low stability. Therefore, we have sought ways of overcoming these limitations and milk proteins pl...

16 Starches with different amylopectin contents and different molecular sizes prepared 17 using acid hydrolysis were hydrophobically modified using octenylsuccinic anhydride 18 (OSA). The OSA-modified starches were used as surfactants to stabilize emulsions of 19 β-carotene and canola oil dispersed in water. The objective of this study is to 20 investigate the relationship between starch molecu...

208 The natural food colorants, carotenoids, are of great importance to human health. The scientists at Department of Agricultural, Food and Nutritional Science, University of Alberta, Canada enhanced the efficiency of SC-CO 2 extraction of carotenoids from carrots, by using canola oil as a continuous cosolvent. The carotenoid content of the starting material was determined by traditional solve...

To quantify the association between dietary and circulating carotenoids and fracture risk, a meta-analysis was conducted by searching MEDLINE and EMBASE databases for eligible articles published before May 2016. Five prospective and 2 case-control studies with 140,265 participants and 4,324 cases were identified in our meta-analysis. Among which 5 studies assessed the association between dietar...

Solubility prediction of high molecular weight molecules in high-pressure solvents is an interesting field of research. Sometimes the solubility data are not available for several components due to lacking of valid equipments. Therefore, an accurate prediction technique can help the researchers. According to the literature, the simple Equations of State (EoSs) such as Soave-Redlich-Kwong (SRK),...

Incorporation of functional foods and nutraceuticals such as carotenoids which suffer from poor water solubility and low bioavailability into nano-sized delivery systems can improve their solubility, stability and oral bioavailability. The aim of this study was to prepare β-Carotene nanodispersion and investigate the effects of preparation parameters by means of response surface methodology usi...