background: the aim of this study was to evaluate maternal and perinatal outcomes in preeclampsia (pe), according to the value of albumin.materials and methods: preeclamptic women were retrospectively divided into mild hypoproteinemia (mhp, n = 220) and severe hypoproteinemia (shp, n = 79) pe according to the value of albumin. the maternal and perinatal outcomes were evaluated in both groups. r...

background: preeclampsia is a disorder of pregnancy without any specific reasons that characterized by high blood pressure and large amounts of protein in the urine. this disorder is caused by multiple factors and finding any factor related to this disorder can help on time prevention of this disease. objective: in this study, serum levels of calcium (ca), magnesium (mg) and zinc (zn) were eval...

a 32-year-old female, gravid two, para one, with cushing’s syndrome (cs) was admitted to our hospital at 25 week of gestation with severe hypercortisolism. basal urinary free cortisol (ufc) was elevated about 10 times above the upper limit of normal in two separate times and plasma cortisol failed to suppress after an overnight 1mg dexamethasone suppression test but adrenocorticotropic hormone ...

OBJECTIVE To determine the association between high hemoglobin with gestational diabetes mellitus (GDM) and preeclampsia in pregnant women in the first trimester. METHODS This cohort study was conducted among 973 pregnant women who started their antenatal booking in the first trimester (first 14 weeks of gestation). Women with first-visit high Hb levels (> 12.5 g/L) on first visit of the preg...

BACKGROUND Long non-coding RNAs (lncRNAs) are an important class of pervasive genes involved in a variety of biological functions. They are aberrantly expressed in many types of diseases. In this study, we aimed to investigate the lncRNA profiles in preeclampsia. Preeclampsia has been observed in patients with molar pregnancy where a fetus is absent, which demonstrate that the placenta is suffi...

Preeclampsia (PE), a hypertension condition associated with pregnancy that manifests after 20 weeks of pregnancy,may be brought on by faulty placental development and poses serious risk to both the mother fetus. The disease can bedetected only once symptoms arise, there is need for biomarker, which makes early detection possible, andproper management done at an stage pregnancy. Even though many...

Background: Preeclampsia is one of the most common complications of pregnancy. It is the cause of high morbidity and mortality for mothers and fetuses, especially in developing countries. The etiology of preeclampsia is unknown. One of the hypothesis on pathophysiology of preeclampsia is dyslipidemia. The aim of this study was to determine maternal plasma levels of lipoproteins in patients with...

The aim of the present study was to explore the levels of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the maternal umbilical serum, placenta and decidua of patients with preeclampsia compared with those in normotensive pregnant females. A total of 73 pregnant females were recruited as the test subjects, including 43 inpatients with hypertensive dis...

Preeclampsia is characterized by development of high blood pressure and proteinuria. It affects 5–8% of all pregnancies and is a major contributor to maternal and fetal morbidity and mortality. In Saudi Arabia, the incidence of preeclampsia is extrapolated to 13,876 out of a population of 25,795,938.In view of increasing number of preeclamptic cases in women of Riyadh, Saudi Arabia, the objecti...

The pregnancy is a physiological metabolic syndrome and women have to pass this stress test to continue a safe life journey, otherwise consequences of this failure will put harmful burden on cardiovascular system of these women. We have chosen the main critical high risk changes affecting pregnant women which are the preeclampsia, gestational Diabetes Mellitus, giving birth to low weight babies...