Abstract Background and Objective: According to the issue of dependence and tolerance in addicted patients, the inefficiency of existing treatments and the new recommendation for drug combination therapy for diseases in modern pharmacology, the present study examined the effect of methadone and valproate combination on morphine dependence and tolerance. Materials and Methods: Ninety-eight male ...

We study the coding potential of human DNA sequences, using the positional asymmetry function (D(p)) and the positional information function (I(q)). Both D(p)and I(q)are based on the positional dependence of single nucleotide frequencies. We investigate the accuracy of D(p)and I(q)in distinguishing coding and non-coding DNA as a function of the parameters p and q, respectively, and explore at w...

Laboratory measurements of the upward intensity distribution in young thin sea ice illustrate the variation of this distribution and peak intensity with growth temperature and ice thickness.

We experimentally investigate the temperature dependence of Rabi oscillations and Ramsey fringes in superconducting phase qubits. In a wide range of temperatures, we find that both the decay time and the amplitude of these coherent oscillations remain nearly unaffected by thermal fluctuations. In the two-level limit, coherent qubit response rapidly vanishes as soon as the energy of thermal fluc...

We study the dependence of the Kolmogorov widths of a compact set on the ambient Banach space.

There is no agreement among palaeobiologists or biologists as to whether, or to what extent, there are limits on diversification and species numbers. Here, we posit that part of the disagreement stems from: (i) the lack of explicit criteria for defining the relevant species pools, which may be defined phylogenetically, ecologically or geographically; (ii) assumptions that must be made when extr...

The sensitivity of the spin dependence of high energy pp scattering, particularly the asymmetry A N N , to the odderon is demonstrated. Several possible ways of determining the spin dependence of the odderon coupling from small-t data are presented.

The influence of temperature on the indentation size effect is explored experimentally. Copper is indented on a custom-built high-temperature nanoindenter, at temperatures between ambient and 200 0C, in an inert atmosphere that precludes oxidation. Over this range of temperatures, the size effect is reduced considerably, suggesting that thermal activation plays a major role in determining the l...