CONTEXT Cannabis-induced psychosis is considered a distinct clinical entity in the existing psychiatric diagnostic systems. However, the validity of the diagnosis is uncertain. OBJECTIVES To establish rate ratios of developing cannabis-induced psychosis associated with predisposition to psychosis and other psychiatric disorders in a first-degree relative and to compare them with the correspon...

The four cases of N-methyl-D-aspartate (NMDA) receptor antibody encephalitis with associated psychosis reported in December raise an important and emerging issue and highlight that psychiatrists should include the condition in the differential diagnosis for patients presenting with acute psychosis. But there are some aspects that need clarification. The authors state that ‘this case series demo...

The four cases of N-methyl-D-aspartate (NMDA) receptor antibody encephalitis with associated psychosis reported in December raise an important and emerging issue and highlight that psychiatrists should include the condition in the differential diagnosis for patients presenting with acute psychosis. But there are some aspects that need clarification. The authors state that ‘this case series demo...

BACKGROUND Treatment delay in first episode psychosis is common. As general practitioners are the first point of contact for many individuals with first episode psychosis, they are well placed to detect the early symptoms and make urgent referrals to specialist secondary care services. However, early psychosis is often difficult to detect. The primary objective of the Redirect trial is to estim...

The four cases of N-methyl-D-aspartate (NMDA) receptor antibody encephalitis with associated psychosis reported in December raise an important and emerging issue and highlight that psychiatrists should include the condition in the differential diagnosis for patients presenting with acute psychosis. But there are some aspects that need clarification. The authors state that ‘this case series demo...

AIMS Few studies have compared time trends for the incidence of psychosis. To date, the results have been inconsistent, showing a decline, an increase or no significant change. As far as we know, no studies explored changes in prevalence of early risk factors. The aim of this study was to investigate differences in early risk factors and cumulative incidences of psychosis by type of psychosis i...

CONTEXT The strong association between lower IQ and risk for psychosis has led to the suggestion that the search for genes influencing cognition may provide a useful strategy for examining the genetic origins of psychosis. However, research in this area has generally used designs in which twin pairs are selected by case status and with assessment of IQ after the onset of psychosis rather than l...

In this study we introduce a few examples intended to illustrate the wide variety of objec­tive correlations that have been established between psyche and muscle tone. These exam­ples illustrate how muscle tone may cause the induction of certain effective or emotional be­haviour patterns, and vice versa.

OBJECTIVE Psychosis or mania after childbirth is a psychiatric emergency with risk for suicide and infanticide. METHOD The authors reviewed the epidemiologic and genetic research and physiological postpartum triggers (endocrine, immunological, circadian) of psychosis. They also summarized all systematic reviews and synthesized the sparse clinical studies to provide diagnostic recommendations,...

BACKGROUND Childhood abuse is considered one of the main environmental risk factors for the development of psychotic symptoms and disorders. However, this association could be due to genetic factors influencing exposure to such risky environments or increasing sensitivity to the detrimental impact of abuse. Therefore, using a large epidemiological case-control sample, we explored the interplay ...