â  zygomycosis is regarded as a rare fetal infection in diabetics and other immunocompromised patients. the usual manifestations of this infection are: rhinosinusitis, pansinusitis, rhino-orbital and rhiâ­nocerebral. primary gastrointestinal (gi) zygomycosis is a rare disâ­ease with a high mortality rate. the stomach is the most common site involved in gi mucormycosis. there are few reported ca...

Rhino-orbital-cerebral zygomycosis afflicts primarily diabetics and immunocompromised individual, but can also occur in normal hosts rarely. We here presented an interesting case of facial nerve palsy and multiple cold abscesses of neck due to rhino-orbital-cerebral zygomycosis in an otherwise healthy man. Although some reports of facial nerve paralysis in conjunction with rhino-orbital-cerebra...

Zygomycosis is a rare invasive opportunistic fungal infection that occurs in the setting of hematologic malignancies, chemotherapy-induced neutropenia, and immunosuppressive therapies. We report the first case of disseminated appendiceal zygomycosis due to Absidia spp. in a neutropenic patient who initially presented as acute appendicitis. A 63-year-old woman with acute myeloid leukemia present...

Zygomycosis is a rare infection in neonates. The clinical presentation is non-specific and diagnosis most often is made at autopsy. Surgical debridement performed early improves survival. We report a case of neonatal zygomycosis with gastric perforation.

The proportion of patients with hematological malignancies (HM) who develop rare invasive fungal infections (IFI) has increased worldwide over the past few decades. Zygomycosis is an opportunistic fungal infection, which begins in the nose and paranasal sinuses due to inhalation of fungal spores. Rhino-cerebral zygomycosis is the most common form of the disease, it typically develops in diabeti...

Breakthrough zygomycosis are increasingly reported life-threatening complications among patients with hematological malignancies, especially since the use of broad spectrum antifungal treatments like voriconazole. We report two cases of breakthrough zygomycosis after caspofungin exposure, with a review of literature.

Pulmonary zygomycosis is an uncommon infection that occurs mostly in immunocompromised patients. We report the case of a 75-year-old man with myelodysplastic syndrome, treated with lenalidomide for 3 months, who developed respiratory failure and a rapidly progressive left upper lobe consolidation. An extensive workup was unrevealing of the etiology, and the patient expired. A full autopsy was ...

Voriconazole is active against Aspergillus and other filamentous fungi, but it has no activity against Zygomycetes. Iowa and Boston groups reported an increase in the incidence of zygomycosis in patients given prophylactic voriconazole. Long-term use of voriconazole might exert selective pressure for growth of resistant organisms however, reviews of data from several transplantation centers sho...

Zygomycosis is an increasing threat to patients with human immunodeficiency virus (HIV) infection. Zygomycosis (formerly called mucormycosis) is the fungal infection with Mucor, Rhizopus, or other species that share a common morphology of large empty pauciseptate hyphae with rare random-angle branching and a collapsed "twisted ribbon" appearance. Morphology allows a specific diagnosis on frozen...