Periodontitis is caused by the inflammation of tooth-supporting tissue pathogens such as Aggregatibacter actinomycetemcomitans. Interleukin-1β (IL-1β), a pro-inflammatory cytokine, triggers series inflammatory reactions and promotes bone resorption. The aim this study was to examine molecular mechanism anti-inflammatory function zingerone, dietary phenolic found in Zingiber officinale, on perio...

Zingerone possesses the potential to relieve asthma via upregulating AMPK/Nrf2/HO-1 signaling pathway.

Zingerone enhances glutamatergic spontaneous excitatory transmission by 1 activating TRPA1 but not TRPV1 channels in the adult rat substantia gelatinosa 2 3 Hai-Yuan Yue, Chung-Yu Jiang, Tsugumi Fujita, and Eiichi Kumamoto 4 5 Department of Physiology, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan 6 7 Running head: glutamatergic transmission enhancement by zingerone 8 9 Number of f...

Prostatic complications are common in patients with diabetes. This study investigated the effect of different ginger ingredients: zingerone, geraniol, and 6-gingerol on the prostate in diabetic rats. Diabetes was induced in Wistar rats by streptozotocin intraperitoneal injection (50 mg/kg), and the rats were left for 10 weeks to develop prostatic complications. In diabetic treated groups, rats ...

Ginger (Zingiber officinale) is a common kitchen spice that belongs to the family Zingiberaceae. It rich in phytochemistry promoting health benefits. used as home remedy support cold, headaches, and pharmacological properties such anti-inflammatory, antioxidant, antiemetic, antiulcer, anti-cancer, antiplatelet, anti-diabetic lipid-lowering activities. Gingerols are key ingredients found ginger ...

Selected synthesized natural and natural-like hydroxylated biphenyls (dimers) and their corresponding monomers (dehydrozingerone, zingerone and ferulic acid) were tested experimentally for their capacity both as radical scavengers and chain-breaking antioxidants in individual and binary mixture with α-tocopherol. Quantum-chemical calculations at the UB3LYP/6-13+G(d,p) level were used to get ful...

Nausea and emesis are a major side effect and obstacle for chemotherapy in cancer patients. Employ of antiemetic drugs help to suppress chemotherapy-induced emesis in some patients but not all patients. Ginger, an herbal medicine, has been traditionally used to treat various kinds of diseases including gastrointestinal symptoms. Ginger is effective in alleviating nausea and emesis, particularly...

Effects of different freezing rates and four different thawing methods on chemical composition, microstructure, and color of ginger were investigated. Computer simulation for predicting the freezing time of cylindrical ginger for two different freezing methods (slow and fast) was done using ANSYS (®) Multiphysics. Different freezing rates (slow and fast) and thawing methods significantly (P < 0...