objective: thalassemic patients are at risk of zinc deficiency due to various causes including desferal injection, hyperzincuria, high ferritin levels, and hepatic iron overload. we evaluate the effect of zinc supplementation on linear growth of beta-thalassemia patients. methods: one-hundred beta-thalassemic major patients whose heights were within 3rd to l0th percentile were randomly divided ...

Objective: Thalassemic patients are at risk of zinc deficiency due to various causes including desferal injection, hyperzincuria, high ferritin levels, and hepatic iron overload. We evaluate the effect of zinc supplementation on linear growth of beta-thalassemia patients. Methods: one-hundred beta-thalassemic major patients whose heights were within 3rd to l0th percentile were randomly divided ...

The extraction and separation of copper(II), zinc(II), cobalt(II), and cadmium(II) were investigated. Both copper(II) and zinc(II) formed ammine-complexes, while cadmium(II) and cobalt(II) formed hydroxide precipitates in an ammonia medium. By the addition of sodium dodecylsulfate (SDS), a copper(II) complex formed an ion-pair (copper-ammine-DS), which was extracted into the SDS phase. However,...

Zinc oxide nanosheet is assessed as a selective adsorbent for the detection and adsorption of cadmium using simple eco-friendly extraction method. Pure zinc oxide nanosheet powders were characterized using field emission scanning electron microscopy, energy dispersive spectroscopy, X-ray diffraction, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy. The zinc oxide n...

a selective and sensitive method for determination of cadmium and zinc is presented. the method is based on adsorptive accumulation of the complexes of cd (ii) and zn (ii) ions with 4-amiono-5-methyl-2,4-dihydro-3h-1,2,4-triazol-3-tion (mmtt) onto hanging mercury drop electrode (hmde), followed by reduction of the adsorbed species by voltammetric scan using differential pulse modulation. the li...

Zinc-dependent superantigens can be divided into two subfamilies based on how they use zinc ions for interactions with major histocompatibility complex (MHC) class II molecules. Members of the first subfamily use zinc ions for interactions with histidine 81 on the beta-chain of MHC class II molecules, whereas members of the second subfamily use zinc ions for dimer formation. The zinc-binding mo...

The effects of zinc and manganese on the reductive dissolution of hematite by the dissimilatory metal-reducing bacterium (DMRB) Shewanella putrefaciens CN32 were studied in batch culture. Experiments were conducted with hematite (2.0 g L 1) in 10 mM PIPES (pH 6.8), and H2 as the electron donor under nongrowth conditions (108 cell mL 1), spiked with zinc (0.02–0.23 mM) or manganese (0.02–1.8 mM)...

The nutritional essentiality of zinc for the growth of living organisms had been recognized long before zinc biochemistry began with the discovery of zinc in carbonic anhydrase in 1939. Painstaking analytical work then demonstrated the presence of zinc as a catalytic and structural cofactor in a few hundred enzymes. In the 1980s, the field again gained momentum with the new principle of "zinc f...

The binding of zinc(II) ions to apo-(bovine erythrocytes superoxide dismutase) was studied by 1H n.m.r. spectroscopy. Two zinc(II) ions bind to each subunit of the apoenzyme, and the first has a binding constant at least an order of magnitude larger than the second. The nature of the spectral changes that occur on binding the first zinc(II) ion are interpreted in terms of a change in the struct...

Almost all naturally occurring metalloproteases are monozinc enzymes. The zinc in any number of zinc metalloproteases has been substituted by some other divalent cation. Almost all Co(II)- or Mn(II)-substituted enzymes maintain the catalytic activity of their zinc counterparts. However, in the case of Cu(II) substitution of zinc proteases, a great number of enzymes are not active, for example, ...