نتایج جستجو برای: zebrafish
تعداد نتایج: 26985 فیلتر نتایج به سال:
Introduction Zebrafish ( Danio rerio ) has evolved over the years as a preferred organism due to its vast repertoire in research fields that mimic targeted phenotype, particularly behavioral typologies and specific attributes comparable murine models relatively high homology with humans. Considering this consideration, different pharmacological treatments have been tested proven under concentra...
Tyrosinase is a key enzyme in melanin production. Therefore, tyrosinase inhibitors are used in cosmetic and medicinal industries to prevent or treat overproduction of melanin such as melasma, solar lentigo and post inflammatory melanoderma. Due to safety of natural whitening agents, in the present study, in-vitro anti-tyrosinase and in-vivo anti-melanogenesis activities of some selected red mac...
The anti-hypercholesterolemic effect of berbamine (BBM) isolated from Rhizoma Coptidis (RC) was investigated in hypercholesterolemic zebrafish model induced by high-cholesterol (HC) diet. Zebrafish embryo assay revealed no significant difference in morphology and cell death with the treatment of BBM less than 20 μg/mL. In zebrafish larvae, the fluorescently labeled cholesterol in caudal artery ...
The aim of this study was to investigate the possibility of hyperglycemia in Zebrafish by adding glucose monohydrate directly to the water of its habitat. A group of 60 Zebrafish were collected from stock tanks of Zebrafish lab core facility in Endocrinology and Metabolism Research Institute (EMRI), and randomly divided into 6 tanks in two treatments with glucose and without glucose (control) i...
بیش از نیمی از مهره داران را انواع ماهیان استخوانی تشکیل می دهند. یک ویژگی اصلی ماهیان استخوانی از نظر تکاملی ، موفقیت در مکانیسم تولیدمثلی آنها است که با شرایط متفاوت محیط آبی سازگار شده است. تخمک ماهیان استخوانی به وسیله لایه فاقد سلول به نام زونا ردیاتا(zr) احاطه می شود. مورفولوژی زونا ردیاتا بین گونه ها متنوع است و سازش به شرایط اکولوژیکی را منعکس می کند. جنبه های مورفولوژیک زونا ردیاتا برا...
This study aimed to investigatethe changes in Gonad Somatic Index (GSI), vitellogenin induction and ovarian histopathology in zebrafish (Danio rerio) adult female, as an ecological model in toxicology, after exposure to 0.002, 0.02, 0.2, 2 and 20 µg/L cadmium chloride for 21 days under sub-lethal condition. The results showed that 0.002 to 20 µg/L cadmium chloride had no significant effect on t...
Today, nanotechnology is recognized as one of the leading sciences in the world, which manipulates atoms and molecules in order to produce valuable products. Extensive use of nanomaterials in various industrial sectors has increased the possibility of their diffusion in water bodies and the environment. Therefore, the study of toxicity of these substances is considered as one of the research ne...
The Zebrafish is a preeminent model organism that, with its most prominent features, has expanded the boundaries of science in many disciplines. Characteristics of this small freshwater fish, with the help of biologists, showed that it has a highly comparable genetic with mammals such as mice and rats. For example, the emergence of new and efficient methods for duplicating and editing the genom...
the present study was conducted to evaluate the effect of dietary inclusion of silver nanoparticle on general performance and digestive proteases in zebra fish. four experimental diets were designed with a concentration of 5, 20 and 40 parts per billion (ppb) nanoparticles in the diet (named s5, s20, and s40, respectively) and control group without any nanoparticles (s0). there was no significa...
Current and proposed standards for commercial breeding of Danio rerio and other ornamental fish for production in laboratories and farms are different and require indigenize with the specific conditions of each production unit. But the general framework of zebrafish farming as a popular ornamental species and laboratory model has been reviewed by bioscientists for many years and can be consider...
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