نتایج جستجو برای: yeast nucleotide

تعداد نتایج: 215540  

Journal: :Nature Communications 2021

Abstract Embryonic aneuploidy from mis-segregation of chromosomes during meiosis causes pregnancy loss. Proper disjunction homologous requires the mismatch repair (MMR) genes MLH1 and MLH3 , essential in mice for fertility. Variants these can increase colorectal cancer risk, yet reproductive impacts are unclear. To determine if MLH1/3 single nucleotide polymorphisms (SNPs) human populations cou...

Journal: :Protein science : a publication of the Protein Society 2009
Kristin A Krukenberg Ulrike M K Böttcher Daniel R Southworth David A Agard

The molecular chaperone, Hsp90, is an essential eukaryotic protein that assists in the maturation and activation of client proteins. Hsp90 function depends upon the binding and hydrolysis of ATP, which causes large conformational rearrangements in the chaperone. Hsp90 is highly conserved from bacteria to eukaryotes, and similar nucleotide-dependent conformations have been demonstrated for the b...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1969
B S Dudock G Katz E K Taylor R W Holley

The complete nucleotide sequence of wheat germ phenylalanine transfer RNA (tRNA(Phe)) is presented. This RNA, which is an acceptable substrate for yeast phenylalanine tRNA synthetase, has a structure very similar to that of yeast tRNA(Phe). Only 16 of the 76 nucleotides are different, and all but two of the nucleotide changes are located in regions that are doublestranded in the cloverleaf mode...

Journal: :The Journal of biological chemistry 1951
G SCHMIDT R CUBILES N ZOLLNER L HECHT N STRICKLER K SERAIDARIAN M SERAIDARIAN S J THANNHAUSER

In an earlier investigation from this laboratory (I), prostatic phosphomonoesterase was used for the partition of the phosphomonoester and phosphodiester groups in ribonuclease digests. It was shown that the inorganic phosphate formed during incubation of ribonuclease digests with phosphatase originated practically exclusively from the acid-stable (pyrimidine) nucleotide groups of ribonucleic a...

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