نتایج جستجو برای: xenoestrogen
تعداد نتایج: 193 فیلتر نتایج به سال:
Bisphenol A (BPA) is a xenoestrogen known for its implications the endocrine systems and several other organs, including kidneys. Recent renal studies have shown that BPA can induce alterations of cytoskeleton cell adhesion mechanisms such as podocytopathy with proteinuria hypertension, involved in progression diseases. These data fact to be present urine almost entire population strongly sugge...
BACKGROUND Most studies on endocrine-disrupting chemicals and breast cancer have focused on single compounds and have produced inconclusive findings. OBJECTIVES We assessed the combined estrogenic effects of mixtures of xenoestrogens in serum and their relationship to breast cancer risk. METHODS A total of 186 incident pretreatment breast cancer cases and 196 frequency-matched controls were...
It has been hypothesized that environmental estrogens may play a role in the increasing incidence of breast cancer, testicular cancer, and other problems of the reproductive system. While a single causal agent can be identified in cases in which humans have had occupational exposures, wildlife showing signs of reproductive damage have usually been exposed to a combination of endocrine disruptor...
The presence of plastic polymers in dental composites has caused uncertainty in the minds of people who are suspicious of the potential impact of plastics on human health. In particular, one component of composite resins, bisphenol-A (BPA), has attracted attention because it can act as a xenoestrogen. For better or for worse, all dental materials are non-biological chemicals, and the only way w...
Xenoestrogens (XEs) are chemicals derived from a variety of natural and anthropogenic sources that can interfere with endogenous estrogens by either mimicking or blocking their responses via non-genomic and/or genomic signaling mechanisms. Disruption of estrogens' actions through the less-studied non-genomic pathway can alter such functional end points as cell proliferation, peptide hormone rel...
Environmental xenoestrogens can be divided into natural compounds (e.g. from plants or fungi), and synthetically derived agents including certain drugs, pesticides and industrial by-products. Dietary exposure comes mainly from plant-derived phytoestrogens, which are thought to have a number of beneficial actions. However, high levels of exogenous estrogens including several well-known synthetic...
The low potency of many man-made estrogenic chemicals, so-called xenoestrogens, has been used to suggest that risks arising from exposure to individual chemicals are negligible. Another argument used to dismiss concerns of health effects is that endogenous steroidal estrogens are too potent for xenoestrogens to contribute significantly to estrogenic effects. Using a yeast reporter gene assay wi...
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