Rhodopsin is formed by the condensation of opsin with a cis isomer of retinene, called neo-b. The bleaching of rhodopsin releases all-trans retinene which must be isomerized back to neo-b in order for rhodopsin to regenerate. Both retinene isomers are in equilibrium with the corresponding isomers of vitamin A, through the alcohol dehydrogenase system. An enzyme is found in cattle retinas and fr...

What happens when machines become more intelligent than humans? One view is that this event will be followed by an explosion to evergreater levels of intelligence, as each generation of machines creates more intelligent machines in turn. This intelligence explosion is now often known as the ‘singularity’. The basic argument here was set out by the statistician I.J. Good in his 1965 article ‘Spe...

Purpose – To show that the neo-pragmatist position of Richard Rorty, when combined with a sociocultural perspective, provides library and information science (LIS) with a forceful epistemological tool. Design/methodology/approach – Literature-based conceptual analysis of: historical development of pragmatism in relation to other epistemological positions; neo-pragmatism as a non-dualist, both p...

In this paper we investigate the notion of developing generic aspects in Hyper/J and compare it with other approaches.

We have developed a new antimetastatic chemotherapeutic strategy for combination with hepatic resection of human colon cancers in a high-metastasis nude mouse model. The new procedure involves i.p. administration of 5-fluorouracil (5-FU) 2 h before hepatic resection of the human colon tumors, with therapy continued postoperatively for 4 consecutive days. We termed this strategy neo-neoadjuvant ...

OBJECTIVES Our objectives were to test whether Conscientiousness, the other 4 domains of the Five-Factor Model, and their facets predicted mortality in older, frail individuals. METHODS Controlling for demographic and health measures, we used Cox regression to test whether the NEO Five-Factor Inventory (NEO-FFI) Neuroticism, Extraversion, Openness to Experience, Agreeableness, and Conscientio...

Galectin inhibitor design is an emerging research field due to the involvement of galectins in cancer. Galectin-3, in particular, plays an important role in tumor progression. To generate inhibitors, modifications of the glycan structure can be introduced. Conjugation of hydrophobic compounds to saccharides has proven to be promising as increased binding of galectin-3 can be observed. In the pr...

the both atlantic side relations from the ancient time had been faced with too much challenge but the continuing of this relation is due to the common political and economical interests. the upper atlantic and the two organizations (nato, eu) still exist to gain the essential goals and the political and security connection which are boosting with the economical integration at the same time. but...

Preand probiotics (synbiotics) are suggested to have beneficial effects on human health. This study describes effects of an amino acid based formula (AAF) with synbiotics in infants with cow’s milk allergy (CMA). In a prospective, randomized, double-blind controlled study, full term infants with diagnosed IgE and/or non-IgE mediated CMA received a commercially available AAF (NEO; n=56) or an AA...