conclusions with growing cohort of young and middle-aged people, there is a probable risk of upsurge of ard. presently, there are dilemmas over the diagnosis of independent ard. thus, there is a need to develop evidence-based guidelines for diagnosis and management of ard through further systematic studies. results the prolonged and excessive use of alcohol may lead to structural and functional...

Thiamine (vitamin B1) deficiency causing Wernicke encephalopathy occurs most frequently in people with compromised absorption (e.g., malnutrition, hyperemesis), increased metabolism (e.g., sepsis, malignancy) or increased carbohydrate intake (e.g., administration of intravenous dextrose). Guidelines from the European Federation of Neurological Societies suggest that Wernicke enceph alopathy is ...

Wernicke encephalopathy consists of a triad of ophthalmoplegia, ataxia, and altered mental status. It is caused by thiamine deficiency and although it is commonly seen in alcoholics, patients undergoing gastric bypass surgery for morbid obesity could be a new group of patients to watch for. Florid papilloedema and optic neuropathy are not commonly seen but are still consistent with the diagnosi...

BACKGROUND Wernicke encephalopathy is caused by thiamine (vitamin B1) deficiency. It is generally considered to be a disease of adult alcoholics. However, it is known to occur in the pediatric population and in non-alcoholic conditions. DATA SOURCES We searched PubMed with the key words Wernicke, thiamine, pediatric, children and adolescents and selected publications that were deemed appropri...

BACKGROUND AND PURPOSE Wernicke encephalopathy is a severe neurologic disorder that results from a dietary vitamin B1 deficiency. It is characterized by changes in consciousness, ocular abnormalities, and ataxia. This study was undertaken to analyze and compare findings on MR imaging and neurologic symptoms at clinical presentations of patients with Wernicke encephalopathy with and without a hi...

Anorexia nervosa presenting as Wernicke-Korsakoff syndrome is rare. The causes of Wernicke-Korsakoff syndrome are multiple like alcohol abuse, thyrotoxicosis, haemodialysis, severe malnutrition because of gastric carcinoma and pyloric obstruction, hyperemesis gravidarum, and prolonged parenteral feeding. We report a case of anorexia nervosa, who presented with Wernicke's encephalopathy and prog...

Aims: A translation into English of the case history section of Carl Wernicke’s original manuscript of 1881, with a discussion on its relevance for clinicians today. Methods: A copy of Carl Wernicke’s original German text was obtained by one of the authors (CCHC) and translated into English from the old German by a professional translator. Results: The translation was subsequently agreed by nat...

Brain stem auditory evoked responses (BAERs) were performed on 25 alcoholic patients with Wernicke-Korsakoff syndrome, 56 alcoholic patients without Wernicke-Korsakoff syndrome, 24 of whom had cerebellar ataxia, and 37 control subjects. Abnormal BAERs were found in 48% of patients with Wernicke-Korsakoff syndrome, in 25% of alcoholic patients without Wernicke-Korsakoff syndrome but with cerebel...

BACKGROUND Gastric partitioning is a surgical procedure for the treatment of morbid obesity that may engender neurological complications, such as Wernicke encephalopathy and polyneuropathy. SETTING A specialist hospital. PATIENT A 36-year-old woman developed Wernicke-Korsakoff encephalopathy and polyneuropathy 3 months after gastroplasty for morbid obesity. A magnetic resonance scan documen...