Networks within our spinal cord generate the basic pattern underlying walking. Over the past decade, much progress has been made in our understanding of their function in a variety of vertebrate species. A significant hurdle has been the identification of candidate populations of neurons that are involved in pattern generation in the spinal cord. Recently, systems neuroscientists in collaborati...

Extracting karyocytes and their components from microscopic bone marrow images is prerequisite for computer-aided early diagnosis of hemopathy. Most existing methods assume all pixels belonging to a karyon region or a cytoplasm region have similar colors. Practically, the color of neither a karyon nor a cytoplasm in a microscopic image is homogeneous in the pixel level. Therefore, the regional ...

Background: Tinnitus known as a central nervous system disorder is correlated with specific oscillatory activities within auditory and non-auditory brain areas. Several studies in the past few years have revealed that in the most tinnitus cases, the response pattern of neurons in auditory system is changed due to auditory deafferentation, which leads to variation and disruption of the brain net...

Introduction: Tinnitus known as a central nervous system disorder is correlated with specific oscillatory activities within auditory and non-auditory brain areas. Several studies in the past few years have revealed that in the most tinnitus cases, the response pattern of neurons in auditory system is changed due to auditory deafferentation, which leads to variation of the brain...

Complex ideas are best conveyed through well-designed illustrations. Up to now, computational neuroscientists have mostly relied on box-and-arrow diagrams of even complex neuronal networks, often using ad hoc notations with conflicting use of symbols from paper to paper. This significantly impedes the communication of ideas in neuronal network modeling. We present here Connectivity Pattern Tabl...

BACKGROUND Rheumatoid arthritis (RA) is commonly accompanied by pain that is discordant with the degree of peripheral pathology. Very little is known about the cerebral processes involved in pain processing in RA. Here we investigated resting-state brain connectivity associated with prolonged pain in RA. METHODS 24 RA subjects and 19 matched controls were compared with regard to both behavior...

The JRC demonstrated the feasibility to assess and report in a harmonized manner, forest landscape pattern and fragmentation in Europe, on the basis of an easily reproducible set of indices. Results were used in the Forest EUROPE, UN ECE and FAO joint ministerial reporting process on the protection of forests in Europe where data on forest pattern do not exist from national forest inventories. ...

Intrinsic functional connectivity detected by functional MRI (fMRI) provides a useful but indirect approach to study the organization of human brain systems. An unresolved question is whether functional connectivity measured by resting-state fMRI reflects anatomical connections. In this study, we used the well-characterized anatomy of cerebrocerebellar circuits to directly test whether intrinsi...

The fundamental goal of computational neuroscience is to discover anatomical features that reflect the functional organization of the brain. Investigations of the physical connections between neuronal structures and measurements of brain activity in vivo have given rise to the concepts of anatomical and functional connectivity, which have been useful for our understanding of brain mechanisms an...