population-based genetic association studies have proven to be a powerful tool in identifying genes implicated in many complex human diseases that have a huge impact on public health. an essential quality control step in such studies is to undertake hardy-weinberg equilibrium (hwe) calculations. deviations from hwe in the control group may reflect important problems including selection bias, po...

stearoyl-coa desaturase (scd) is a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids (mufa). a number of studies support the hypothesis that scd gene regulation and polymorphism may affect fatty acid composition and fat quality in meat and milk. single nucleotide polymorphisms in the coding region of the bovine stearoyl-coa desaturase gene have been predicted to result in ...

This study was carried out to investigate the genetic diversity and population structure of 90 specimens of Oxynoemacheilus argyrogramma collected from Sepidbarg, Gamasiab and Ghaleji rivers, in the west of Iran. Analyses using three microsatellite loci indicated that the average number of alleles in the population was 12, which was well above the reported values for freshwater fishes. The expe...

bream (abramis brama orientalis) is one of the most commercially valuable fish in the caspian sea. the aim of this study was to compare levels of genetic polymorphism between wild and farmed bream populations using seven microsatellite loci. genetic diversity was investigated by studying samples collected from two regions; chaboksar and the artificial propagation center of guilan province. alle...

conclusions in conclusion, the ace and pparg genes do not have a key role in conferring risk for diabetic nephropathy. results ace id genotypes followed hardy-weinberg equilibrium in both cases and controls. but p12a genotypes deviated from hardy-weinberg equilibrium in diabetic controls. chi2 test was applied for the analysis of genotypic distributions in genotypic and dominant models. odds ra...