BACKGROUND The 2000 Centers for Disease Control and Prevention growth charts for the United States include population reference data for body mass index (BMI)-for-age (ages 2-19 y) and weight-for-stature (from 77 to 121 cm). For younger children, either set of reference data could be used. OBJECTIVE The objective of this study was to compare BMI-for-age with weight-for-stature. DESIGN We us...

BACKGROUND Longitudinal growth associations with genetic variants identified for adult BMI may provide insights into the timing of obesity susceptibility. OBJECTIVE The objective was to explore associations of known BMI loci with measures of body size from birth to adulthood. DESIGN A total of 2537 individuals from a longitudinal British birth cohort were genotyped for 11 genetic variants r...

BACKGROUND Increasing evidence indicates that adult body composition is associated with prenatal and infancy weight gain, but the relative importance of different time periods has not been elucidated. OBJECTIVE The objective was to study the association between prenatal, early postnatal, and late infancy weight gain and body mass index (BMI), fat mass, and fat distribution in young adulthood....

Patients with neurodegenerative disorders lose body weight as their diseases progress. In Parkinson’s disease (PD), however, autonomic dysfunction is associated with increased body mass index (BMI). We investigated the correlation between BMI, clinical features, and autonomic dysfunction in patients with multiple system atrophy with predominant parkinsonism (MSAP). BMI, clinical features, cardi...

Th e aim of the study was to analyse the changes in BMI category between 7 and 16–18 years of age on the basis of continuous studies and evaluate which factors are related to the increase and decrease in BMI category. Data were collected from 1008 secondary school students aged 16–18 y. Body height and weight were measured and BMI was calculated. Information on height and body mass in earlier p...

Background: Observational studies have shown that higher body mass index (BMI) is associated with increased risk of developing disordered eating patterns. However, the causal direction of this relation remains ambiguous.Objective: We used Mendelian randomization (MR) to infer the direction of causality between BMI and disordered eating in childhood, adolescence, and adulthood.Design: MR analyse...

BACKGROUND Chemicals with endocrine-disrupting abilities may act as obesogens and interfere with the body's natural weight-control mechanisms, especially if exposure occurs during prenatal life. OBJECTIVE We examined the association between prenatal exposure to polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (DDE) and subsequent obesity at 5 and 7 y of age. DESIGN...

BACKGROUND The effectiveness of commercial weight-loss programs consisting of very-low-calorie diets (VLCDs) and low-calorie diets (LCDs) is unclear. OBJECTIVE The aim of the study was to quantify weight loss and dropout during a commercial weight-loss program in Sweden (Itrim; cost: $1300/€1000; all participants paid their own fee). DESIGN This observational cohort study linked commercial ...

Background. Many institutions mandate preoperative weight loss prior to bariatric surgery. This study examines the correlation between preoperative weight change and postoperative success following laparoscopic Roux-en-Y gastric bypass. Methods. We retrospectively studied the correlation between change in BMI before surgery and change in BMI postoperatively, using linear regression analyses and...

AIM To provide growth and sexual maturation reference data for Moroccan children living in The Netherlands and to compare them with the reference data of children of Dutch origin. METHODS Cross-sectional growth and demographic data were collected from 2880 children of Moroccan origin and 14,500 children of Dutch origin living in The Netherlands in the age range 0-20 y. Growth references for l...