OBJECTIVE To estimate the prevalence, annual mortality, and geographic distribution of Wegener's granulomatosis. METHODS Analysis of national vital statistics data and hospitalization data from a national survey and from all New York State inpatient facilities. RESULTS Between 1979 and 1988, 1,784 death certificates in the United States listed Wegener's granulomatosis as a cause of death. N...

Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a necrotizing vasculitis of small and medium-sized blood vessels characterized by diffuse inflammation vascular structures perivascular extravascular granulomatosis. In its systemic form, GPA predominantly affects the ear, nose throat, lung kidney involvement typically rapidly progressive glomerulonephritis e...

1 Kauzman A, Quesnel-Mercier A, Lalonde B. Orofacial granulomatosis: 2 case reports and literature review. J Can Dent Assoc 2006; 72:325–9. 2 Campbell HE, Escudiet MP, Patel P et al. Review article: cinnamonand benzoate-free diet as a primary treatment for orofacial granulomatosis. Aliment Pharmacol Ther 2011; 34:687–701. 3 Giovannetti A, Mazzetta F, Cavani A et al. Skewed T-cell receptor varia...

orofacial granulomatosis(ofg) is a granulomatous disease of the orofacial region which appears usually as a persistent and/or recurrent labial soft tissues swelling in the orofacial region and is characterized histologically by a granulomatous inflammation. ofg may cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. the...

Relevance. Granulomatosis with polyangiitis (Wegener's granulomatosis) is a rare disease in which oral cavity symptoms manifest as 'strawberry' gingivitis. Description of the clinical case. The paper presents early systemic – granulomatosis manifestation gingival hyperplasia 1 patient, form so-called "strawberry gingivitis", another non-specific ulcer on mucous mem-brane soft palate. After exam...

Granulomatosis with polyangiitis (GPA) is characterised by granulomatous necrotising inflammatory lesions of the upper and lower respiratory tract, often associated with pauci-immune glomerulonephritis. The diagnosis of granulomatosis with polyangiitis is made according to the classification criteria of the ACR criteria for granulomatosis with polyangiitis. We present two cases of granulomatosi...

wegener’s granulomatosis is a necrotizing granulomatous vasculitis involving small and medium sized vessels. the syndrome is classically defined as having involvement of kidney, lungs and upper respiratory tract (i.e. sinuses). wegener’s granulomatosis may be present in other autoimmune or inflammatory diseases, particulary systemic lupus erythematosis (sle), but most frequently has been associ...

INTRODUCTION Accurate evaluation of disease status is very important in treatment of Wegener's granulomatosis CASE PRESENTATION A 73-year-old Japanese man presented with chronic sinusitis and otitis media. He was admitted to our hospital because of bilateral lung nodules. Cytoplasmic antineutrophil cytoplasmic antibody was negative but his rheumatoid factor was high. He was diagnosed with lim...

BACKGROUND AND PURPOSE Stroke is an uncommon sequela of Wegener's granulomatosis, resulting primarily from vasculitic infiltration of small to medium-sized vessels. We describe a young patient with Wegener's granulomatosis and basilar artery occlusion. CASE DESCRIPTION A 26-year-old man with histopathologically confirmed Wegener's granulomatosis suffered a brain stem stroke 24 hours after ope...

2. Guiñazú Álvarez A, Matteoda M, Tempra A. Granulomatosis linfomatoidea: manifestaciones pulmonares de una entidad infrecuente. RAR. 2006;70:289–92. 3. Frazier AA, Rosado-de-Christenson ML, Galvin JR, Fleming MV. Pulmonary angiitis and granulomatosis: radiologic–pathologic correlation. Radiographics. 1998;18:687–710. 4. Ammannagari N, Gao Z, Deng C, O’Connor O. Lymphomatoid granulomatosis: a d...