Objective PCOS is the most frequent female endocrine disorder, affecting 5%-10% of women, is characterized by hyperandrogenism, oligo-/anovulation, and polycystic ovaries. The aim of the present research is to evaluate the expression of steroidogenic acute regulatory protein (StAR) and CYP19 (aromatase) mRNA in the ovary of EV-induced PCOS rat model and the effect of the treadmill and running w...

introduction: parkinsonrquote s disease (pd) is a human neurodegenerative disorder which is associated with a massive and progressive degeneration of dopaminergic neurons in subistantia nigra (sn). there is a strong evidence of an oxidative stress participates in the etiology of pd. materials and methods: the rats were divided into sham-operated, experimental and vitamin e-treated groups. for a...

PURPOSE Voluntary loaded wheel running involves the use of a load during a voluntary running activity. A muscle-strength or power-type activity performed at a relatively high intensity and a short duration may cause fewer apparent metabolic adaptations but may still elicit muscle fiber hypertrophy. This study aimed to determine the effects of acute voluntary wheel running with an additional loa...

Progressive loss of dopaminergic neurons in substantia nigra is a key pathogenesis of Parkinson's disease. In the present study, we investigated the effects of treadmill exercise on short-term memory, apoptotic dopaminergic neuronal cell death and fiber loss in the nigrostriatum, and cell proliferation in the hippocampal dentate gyrus of Parkinson's rats. Parkinson's rats were made by injection...

Background. Previous surveys have shown that motor deficits precede the classical motor symptoms seen in Parkinson’s disease (PD) and that physical exercise may have beneficial effects on PD. Objectives. Here, we evaluated the potential of voluntary exercise to improve motor deficit in experimentally-induced Parkinson’s disease (6-OHDA) rats. Methods. Forty adult Wistar rats were ...