OBJECTIVES Recent reports of high endophthalmitis rates after intravitreal triamcinolone acetonide injection have raised concerns about the safety of this treatment. We sought to evaluate the effect of intravitreal triamcinolone injection on (1) the susceptibility to experimental bacterial endophthalmitis and (2) the subsequent therapeutic response to antibiotic treatment. DESIGN For the susc...

A 40-year-old Asian Indian woman, diagnosed as having idiopathic panuveitis (elsewhere) 3 years earlier and being treated with oral steroids (20 mg/day) methotrexate (25 mg/week), presented to us worsening vision in both eyes. Her best corrected visual acuity (BCVA) was perception of light her right eye counting fingers close face left eye. slit lamp examination showed an anterior chamber (AC) ...

PURPOSE The purpose of this study was to evaluate the role of pneumatic retinopexy as an initial management of retinal detachment associated with hypotony, severe choroidal detachment, and vitritis. METHODS Retrospective, interventional, noncomparative case series. We included nine eyes from nine patients (six women and three men) with retinal detachment associated with hypotony, severe choro...

purpose: to report a patient with an intraocular lymphoma with history of treated brain lymphoma. case report: a 45-year-old female was referred with moderate chronic intermediate uveitis of both eyes that was unresponsive to medications. she had history of treated brain lymphoma with chemotherapy and radiotherapy 6 years before presentation. systemic workup, laboratory evaluation, brain and or...

OBJECTIVE To obtain diagnostic guidelines of Fuchs' heterochromic cyclitis (FHC) in the absence of heterochromia using Bayesian methods. METHODS The pre-test and post-test likelihood that a certain patient without heterochromia (but with other characteristic symptoms of the disease such as iris nodules, cataracts, glaucoma or vitritis) has FCH, was assessed by the Bayes' theorem for condition...

EDITOR,—Between 16% and 40% of patients with AIDS develop cytomegalovirus retinitis (CMVR). 2 This typically presents when the CD4+ count drops below 75 cells/μl. Visual loss is usually due to retinal detachment, macular or optic nerve infection, or vascular occlusion. Typically a minimal inflammatory response is mounted. Patients with CMVR not associated with HIV infection may develop a vitrit...

Aim: To assess efficacy and complications of trans-Tenon’s retrobulbar infusion of triamcinolone acetonide for posterior uveitic inflammation. Methods: Non-randomised, uncontrolled, retrospective study of 51 eyes of 37 patients who underwent triamcinolone infusion for vitritis, cystoid macular oedema (CMO), or posterior retinal vasculitis using a long blunt cannula via an incision made through ...

AIM To assess efficacy and complications of trans-Tenon's retrobulbar infusion of triamcinolone acetonide for posterior uveitic inflammation. METHODS Non-randomised, uncontrolled, retrospective study of 51 eyes of 37 patients who underwent triamcinolone infusion for vitritis, cystoid macular oedema (CMO), or posterior retinal vasculitis using a long blunt cannula via an incision made through ...

The complement system is involved not only in host defense against infection but also in autoimmune tissue damage. Using a radioimmunoassay, we sought to measure levels of C3a, C4a and C5a (activated complement fragments with anaphylatoxin functions) in human vitreous humor from eyes with and without vitreal inflammation. Vitreous from 11 patients with clinical evidence of vitritis (Group 2) ha...