BACKGROUND Vitiligo is a chronic skin disorder. White macules caused by melanocyte destruction is a characteristic finding that cosmetically disturbing. Until recently, pathogenesis of vitiligo is still unclear. The role of homocysteine in vitiligo is mentioned in previous studies thus it is probable that it can be a biomarker to determine vitiligo severity. AIM To determine correlation betwe...

BACKGROUND Various studies worldwide suggest that human leukocyte antigen (HLA) region may be involved in the genetic susceptibility of vitiligo but little information is available from India. AIM To find the HLA associated susceptibility to develop vitiligo in Indian patients and to detect role of HLA in familial vitiligo. METHODS This was a case controlled study which included all patient...

The aim of our study was to determine the epidemiological and clinical aspects of vitiligo in the largest dermatology department of Senegal. A cross-sectional and descriptive study in a period of 5 months was performed covering all the vitiligo cases. Fifty patients were identified (26 women and 24 men). The mean age was 26.5 years. A family history of vitiligo was found in 11 cases and a psych...

background: segmental vitiligo is a small subset albeit persistent form of focal vitiligo with dermatomal distribution and resistant to medical therapy. in recent years, surgical therapy as hair follicle autograft transplantation has been a hot topic in management of segmental vitiligo. in this study, we evaluated the efficacy of this method in segmental vitiligo lesions. methods: the study rec...

BACKGROUND The onset of vitiligo during childhood is common. Limited data exist that compare the clinical associations of prepubertal and postpubertal vitiligo in Arabs. OBJECTIVE To compare the clinical profile of pre and postpubertal onset vitiligo. METHODS A cross-sectional observational study was conducted. The Vitiligo European Task Force questionnaire was completed for each patient. ...

Introduction There are a few studies showing an increased risk of insulin resistance, metabolic syndrome, and oxidative stress in patients with vitiligo. Aim To investigate whether systemic inflammation is increased in vitiligo patients in a case-control study design. Material and methods Nonsegmental vitiligo patients who had been followed at the outpatient dermatology clinic of a universi...

PURPOSE Vitiligo prevalence and its associated comorbidities rate have been reported variably among different populations. We aimed to determine the prevalence of vitiligo in Korea along with the baseline rate of comorbidities and compared the risks to the general population using hospital visit information of the total population in Korea. MATERIALS AND METHODS We assessed demographic charac...

Vitiligo vulgaris is an acquired depigmenting disorder resulting from the loss of melanocytes in the skin. Though several putative susceptibility loci of vitiligo have been identified in different populations, the pathogenesis of the disease remains poorly understood. Through genetic linkage analysis of a large Chinese family cohort of vitiligo, we identified a vitiligo linkage locus AIS4 withi...

BACKGROUND Vitiligo is one of many diseases that can be found with diabetes mellitus. Diabetic patients have a high incidence of vitiligo compared to the general population. This study assesses prevalence of vitiligo in type 2 diabetic patients in Iran. METHODS One thousand one hundred type 2 diabetic patients and 1100 healthy adults were recruited in this cross-sectional study. Patients were...

The aetiopathogenesis of vitiligo has not been fully understood. To investigate the role of oxidative stress in pathogenesis of vitiligo, we examined the blood level of antioxidants and malondialdehyde in 40 patients with generalized vitiligo and 40 healthy volunteers belonging to same age group. Our results revealed that the level of malondialdehyde was significantly raised while those of vita...