BACKGROUND & OBJECTIVE Disease burden due to lymphatic filariasis is disproportionately high despite mass drug administration with conventional drugs. Usage of herbal drugs in traditional medicine is quite well known but largely empirical. Hence the present study was designed to screen the in vitro antifilarial effect of four herbal plants on Brugia malayi. METHODS Motility of microfilariae o...

The antifungal activity of eight different medicinal plants namely Aloe vera, Ocimum sanctum, Cenetella asiatica, Piper betle, Calotropis gigantea, Vitex negundo, Ocimum basilicum and Azadirachta indica were tested against plant pathogenic fungus (red rot disease causing agent) Colletotrichum falcatum by agar well –diffusion method. The plants leaves were extracted with various solvents like ch...

RASADAH, M. A., FAREDIAH, A., WONG, C. L. & ONG, B. K. 2005. Antiinflammatory activity of extracts and compounds from Vitex negundo. The antiinflammatory activity of the leaf extract of Vitex negundo was investigated on topical administration using the TPA (tetradecanoylphorbol acetate)-induced mouse ear inflammation model. The crude methanolic extract of V. negundo showed moderate inhibition (...

Objective: Vitex negundo, commonly known as “nirgundi” is widely used in traditional as well as in folk medicines to cure many ailments such as fever, rheumatism, gum and skin diseases and liver disorders, etc. The present study evaluated the antioxidant potency of hydroethanolic extract of Vitex negundo leaves (VNE) in Freund’s complete adjuvant (FCA) induced arthritis. Methods: Acute oral tox...

The preliminary phytochemical analysis of eight medicinal plants from Amravati District (MS) was done. The plants were Abutilon indicum L .(Swart)., Euphrbia hirta L., Ficus hispida L. f., Melia azedarch L., Phyllathus reticulatus Poir. ,Psidium guajava L., vitex negundo L., Vitex pinnata L. Qualitative phytochemical analysis of these plants confirms the presence of various phytochemicals like ...

Supercritical fluid extract and ethanol extract of Vitex negundo Linn. were subjected to the chromatographic evaluation for identification of their constituents. Free radical scavenging activity of both extracts was studied by subjecting them to DPPH assay. IC(50) values of ethanol and supercritical fluid extract of Vitex negundo indicate that ethanol extract has stronger reducing potential and...

Effect of solvent residues of Vitex negundo L. and Cassia fistula L. leaves (0.5 and 1%) was studied on egg laying and adult emergence of Callosobruchus maculatus Fab. and on percentage of larval parasitism by Dinarmus vagabundus (Timberlake). Cowpea seeds treated with methanol and aqueous extract of Vitex, at these concentrations (0.5 and 1%), significantly reduced the number of eggs and emerg...

CONTEXT Vitex negundo Linn. (Verbenaceae) seeds are pepper substitute and occasionally used as a condiment for edible purposes. The seeds also find use for analgesia, sedation, rheumatism and joint inflammation in folk medicine. OBJECTIVE To isolate and characterize bioactive constituents from V. negundo seeds. MATERIALS AND METHODS The ethanol extract of V. negundo seeds was subjected to r...

Many traditionally used plants hold importance in modern days medical regimen as they have been proved scientifically to posses various activity which are desirable, one of such plant is Vitex negundo Linn which is distributed throughout India. It is large aromatic shrub belonging to the family Verbenaceae growing in moist or along the water courses. Phytochemical investigation shows the presen...