نتایج جستجو برای: viral vector

تعداد نتایج: 341208  

ژورنال: کومش 2019
Anjam Najmedini, Ali, Bashash, Davood, Pourbagheri-Sigaroodi , Atieh , Sorourian , Soofia , Vahabpour Roudsari, Rouhollah,

Introduction: Following the first description of multiple myeloma (MM), as the second most prevalent hematologic malignancy, multiple promising advances have paved the way to increase the long-lasting complete remission for patients. In the era of the novel therapeutic approaches, the cloning of the apoptosis-inducing genes into the genome of malignant cells has attracted tremendous attention. ...

2015
Penghua Wang Fengwei Bai Gong Cheng Jianfeng Dai Michael J Conway

1 Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06512, USA 2Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA 3Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China 4 Institute of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soocho...

Journal: :Clinical and Vaccine Immunology 2017

Objective(s): Diabetes mellitus (DM) is a major worldwide public health challenge, for which gene therapy offers a potential therapeutic approach. To date, no systematic review or meta-analysis has been published in this area, so we examined all relevant published studies on rodents to elucidate the overall effects of gene therapy on bodyweight, intraperitoneal glucose...

Background: Safe and effective gene therapy is considered as one of the therapeutic goals in many diseases. Due to the important role of stem cells in cell therapy, this study aimed to produce human adipose-derived mesenchymal stem cells (hASCs) using the miR-34a overexpression. Materials and methods: The hsa-mir-34a precursor sequence was cloned into the PCDH lentiviral vector. The recombinant...

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