A clinical study of vernal keratoconjunctivitis in black children in Southern Africa was conducted to report on the peculiar, predominantly limbal form of the disease, and to test its response to therapy. Pigmented and thickened limbal conjunctiva gave the disease its typical appearance. In severe cases these lesions were encroaching on to the cornea and threatened sight. Placebo had no effect ...

OBJECTIVE To compare the efficacy of 0.1% tacrolimus (FK-506) ophthalmic ointment with 2% cyclosporine eye drops in the treatment of vernal keratoconjunctivitis (VKC). DESIGN Prospective double-masked randomized comparative trial. PARTICIPANTS Twenty-four VKC patients were enrolled into the study. Their mean age was 9.61 +/- 2.55 years. Twelve patients were allocated into the FK-506 group a...

OBJECTIVE To evaluate the effects on signs and symptoms of a coexisting vernal keratoconjunctivitis in patients treated with oral montelukast sodium for asthma. METHODS Twelve patients with vernal keratoconjunctivitis and asthma were enrolled in this pilot study. Topical eyedrops or any systemic treatment was discontinued for at least 7 days before montelukast treatment. Patients were asked t...

Vernal Shield ulcer is a rare sight threatening corneal manifestation of vernal keratoconjunctivitis. This study is designed to report management of a refractory shield ulcer that did not respond to variety of medications but healed in 1 week after surgical debridement of ulcer base. A 12-year old Omani boy with H/O vernal conjunctivitis since 5 years on ketotifen eye drops presented with a shi...