We evaluated the use of pressure support to compensate for the added inspiratory work of breathing due to the resistances of endotracheal tubes and a ventilator demand-valve system for continuous positive airway pressure (CPAP). A mechanical model was used to simulate spontaneous breathing at five respiratory rates through 7-mm, 8-mm, and 9-mm endotracheal tubes with and without a ventilator de...

Aim: The use of positive airway pressure in babies with respiratory failure has been associated significant reductions failure, morbidity, and death. two most popular CPAP techniques are bladder (B-CPAP) ventilator-assisted (V-CPAP). We wanted to see if B-CPAP V-CPAP have different survival rates problems. Methods: This retrospective medical trial included 60 preterm between 1500- 2500 g who we...

OBJECTIVE Application of Continuous Positive Airway Pressure (CPAP) in neonate with respiratory distress is associated with reduction of respiratory failure, reduced complications and mortality. Bubble CPAP (B-CPAP) and ventilator-derived CPAP (V-CPAP) are two most popular CPAP modes. We aimed to determine whether B-CPAP and V-CPAP would have different survival rate and possible complications. ...

Lung-sparing medical ventilation –CPAP + PSV Mode – The FABIAN HFO is a new medical ventilator that was developed mainly for use with newborns and can accommodate children weighing up to 30 kg. It is equipped for ventilation modes CMV, SIMV, AC, PSV, and HFO and has VG, volume limit, and leak correction functions. A key feature is separate pressure setup for backup ventilation during apnoea in ...

Continuous positive airway pressure (CPAP) is a simple, inexpensive and gentle mode of respiratory support in preterm very low birth weight (VLBW) infants. It helps by preventing the alveolar collapse and increasing the functional residual capacity of the lungs. Since it results in less ventilator induced lung injury than mechanical ventilation, it should theoretically reduce the incidence of c...

First, out of 296 infants of respiratory distress syndrome (RDS) requiring continuous positive airway pressure (CPAP), a total of 150 infants required intubation for invasive ventilation and another 53 infants requiring intubation couldn’t be randomized due to nonavailability of designated ventilator. This means that there was a CPAP failure in 69% of the cases. Studies from India itself had sh...

BACKGROUND Bubble continuous positive airway pressure (BCPAP) is a low-cost nasal CPAP delivery system with potential benefits for developing nations. The objective of the study was to compare the efficacy and safety of BCPAP with ventilator CPAP (VCPAP) in preterm neonates with moderate respiratory distress. METHODS In a pilot randomized controlled trial, 30 preterm neonates (gestation <37 w...

The development, manufacturing and deployment of a South African engineered Continuous Positive Airway Pressure Ventilator is described. CSIR L.I.F.E. (Lung Inspiratory Flow Enabler) was developed during the COVID Pandemic in response to need for ventilator solution assist patients suffering from respiratory distress. A supply chain created resulting near fully locally sourced product which 18,...

OBJECTIVE Evaluate the effects of continuous positive airway pressure (CPAP)/positive end-expiratory pressure (PEEP) and pressure support ventilation (PSV) on work of breathing (WOB). METHODS With 13 anesthetized lambs we measured WOB with an esophageal balloon and flow signals. All the animals were sedated, intubated, and ventilated, using 2 pediatric ventilators (Servo 300 and VIP Bird). Ve...

Early continuous positive airway pressure (CPAP) has proven to be beneficial in reducing ventilator dependence and subsequent chronic lung disease in neonates suffering from Respiratory distress syndrome (RDS). However, the efficacy of initiating labour room (LR) CPAP has not been determined prospectively in resource limited settings like India. Hence the objective of the present study was to s...