objective(s):every year, a large number of people lose their lives due to stroke. stroke is the second leading cause of death worldwide. surprisingly, recent studies have shown that preconditioning with hyperoxia (ho) increases tissue tolerance to ischemia, ultimately reducing damages caused by stroke. addressed in this study are beneficial contributions from ho preconditioning into reduced har...

conclusions our study indicated that ace-d and vegf-g alleles can be an independent risk factor for microalbominuria in t2dm patients. results a total of 255 consecutive patients with t2dm and microalbuminuria (group a) and 235 patients with t2dm and normoalbuminuria (group b) were included in the study. in univariate analysis, the groups were statistically similar for all variables, except for...

introduction: angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels. cardiovascular endothelial factors are involved in diseases and vascular regulation.  stachys lavandulifolia belongs to the laminacea family and its hydroalcoholic extract is used as a traditional treatment to reduce pain and inflammation. the present study was conducted to ex...

introduction: pulsed dye laser (pdl) is an important treatment for superficial infantile hemangioma, but few studies report on its cellular mechanism. the aim of this study was to evaluate alterations of serum vascular endothelial growth factor (vegf) level in infantile hemangioma (ih) patients after laser treatment and effects of pdl irradiation on human umbilical vein endothelial cells (huvec...

previous studies have demonstrated that vascular endothelial growth factor (vegf) can trigger angiogenesis as well as inflammation through binding to its membranous receptor-1 on endothelial and inflammatory cells. we aimed to correlate the circulatory number of cells expressing such receptor as well as the serum level of vegf and the soluble form of its receptor-1 (svegfr1) to the severity of ...

background and objectives: angiogenesis is essential for growth and metastasis of solid malignancies. tumor vessel count and expression of vascular endothelial growth factor (vegf), a potent angiogenic factor, have been associated with prognosis. this study was designed to assess vessels density by using cd31 and cd105 (endoglin) and their correlation with expression of vegf and proliferative i...

background: the effects of the vascular endothelial growth factor (vegf) gene ?2578c/a polymorphism on colorectal cancer (crc) risk have been investigated in some studies; however, the results of these studies were conflicting and ambiguous. therefore, we aimed to do a meta-analysis to investigate the association of vegf ?2578c/a polymorphisms with crc risk from all eligible case-control studie...

objective(s):although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hucm) transplantation post myocardial infarction (mi), but this stem cell resource has no potential to induce angiogenesis. in order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hucm ...