نتایج جستجو برای: vacuolation

تعداد نتایج: 1073  

Journal: :The Journal of Cell Biology 1981
S Ohkuma B Poole

With few exceptions, weakly basic compounds that are sufficiently lipophilic in their neutral forms and sufficiently hydrophilic in their protonated forms accumulate in lysosomes. When the concentration within the lysosomes becomes sufficiently high, osmotic swelling occurs. The cells than take on a vacuolated appearance. The concentrations at which different weak bases cause lysosomal vacuolat...

Journal: :British Journal of Ophthalmology 1939

2017
Pablo Granados-Durán María Dolores López-Ávalos Manuel Cifuentes Margarita Pérez-Martín María del Mar Fernández-Arjona Timothy R. Hughes Krista Johnson B. Paul Morgan Pedro Fernández-Llebrez Jesús M. Grondona

AIMS Some central nervous system pathogens express neuraminidase (NA) on their surfaces. In the rat brain, a single intracerebroventricular (ICV) injection of NA induces myelin vacuolation in axonal tracts. Here, we explore the nature, the time course, and the role of the complement system in this damage. METHODS The spatiotemporal analysis of myelin vacuolation was performed by optical and e...

Journal: :The British journal of ophthalmology 1937
B Graves

foundation of the Irish part of this journal was Arthur Jacob, one of the Masters of British Ophthalmology. The centenary number contains a short history of the journal during its hundred years existence by Dr. Rowlette, of Dublin; the paper by Sir StClair Thomson on Victorian age, medical celebrities from the cartoons in Vanity Fair; papers on the last hundred years of medicine, surgery and ob...

Journal: :Journal of Veterinary Diagnostic Investigation 1999

Journal: :British Journal of Ophthalmology 1937

Journal: :Journal of Clinical Pathology 1981

Journal: :The Journal of clinical investigation 2001
J Suzuki H Ohnsihi H Shibata A Wada T Hirayama T Iiri N Ueda C Kanamaru T Tsuchida H Mashima H Yasuda T Fujita

The Helicobacter pylori-produced cytotoxin VacA induces intracellular vacuolation. To elucidate the molecular mechanism of vacuole formation by VacA, we examined the participation of dynamin, a GTPase functioning in intracellular vesicle formation, in human HeLa cells. Immunocytochemistry revealed that endogenous dynamin was localized to vacuoles induced by VacA. In cells transiently transfecte...

Journal: :Egyptian Liver Journal 2021

Abstract Background Tamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which used for prevention treatment influenza. The present study was carried out to evaluate the effect of on liver adult male albino mice from histological ultrastructural points views. Results Histological examination sections treated with included enlargement congestion central hepatic veins in additio...

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