OBJECTIVE To estimate the incremental delivery cost of human papillomavirus (HPV) vaccination of young adolescent girls in Peru, Uganda and Viet Nam. METHODS Data were collected from a sample of facilities that participated in five demonstration projects for hpv vaccine delivery: school-based delivery was used in Peru, Uganda and Viet Nam; health-centre-based delivery was also used in Viet Na...

Conventional parenteral injection of vaccines is limited in its ability to induce locally-produced immune responses in the respiratory tract, and has logistical disadvantages in widespread vaccine administration. Recent studies suggest that intranasal delivery or vaccination in the respiratory tract with recombinant viral vectors can enhance immunogenicity and protection against respiratory dis...

Vaccination is the most efficient method for infectious disease prevention. Parenteral injections such as intramuscular, intradermal, and subcutaneous injections have several advantages in vaccine delivery, but there are many drawbacks. Thus, the development of a new vaccine delivery system has long been required. Recently, microneedles have been attracting attention as new vaccination tools. M...

Last decades, the number of routine childhood vaccinations has increased considerably, which consequently has led to multiple vaccine injections per consultation. Implementation of additional vaccines will probably lead to more than 2 vaccine injections per consult, which might be a barrier for parents to vaccinate their child. A decrease in vaccination coverage, however, increases the risk of ...

*Corresponding author Dr. Wahid Khan, Ph.D Assistant Professor Department of Pharmaceutics National Insititute of Pharmaceutical Education and Research Balanagar, Hyderabad 500 037, Andhra Pradesh, INDIA E-Mail: wahid@niperhyd.ac.in ABSTRACT Success of vaccination in dealing with the communicable diseases can be clearly understood by eradication of smallpox and the imminent decrease of polio, a...

Influenza viruses continue to be a major health threat in human and bird populations. The improvements in formulation and production level of the current influenza vaccines are not sufficient to afford complete protection. The continuous antigenic drifts and emergence of endemic and zoonotic strains make influenza vaccine planning difficult. Concern about the emergence of new influenza pandemic...

Infections of the respiratory and GI tracts are among the most common diseases of piglets worldwide and cause substantial economic loss to swine producers. Effective immunity to these infections needs a specific response at the surface of the tract (Bozic et al., 2002). However vaccine formulation and delivery to these surfaces remains a major challenge. Recent evidence of this type of immune r...

Vaccination has had a major impact on the control of infectious diseases. However, there are still many infectious diseases for which the development of an effective vaccine has been elusive. In many cases the failure to devise vaccines is a consequence of the inability of vaccine candidates to evoke appropriate immune responses. This is especially true where cellular immunity is required for p...