Non-melanoma skin cancer (NMSC) is the most common type of cancer. Increased expression and activity of Rac1, a small Rho GTPase, has been shown previously in NMSC and other human cancers; suggesting that Rac1 may function as an oncogene in skin. DMBA/TPA skin carcinogenesis studies in mice have shown that Rac1 is required for chemically induced skin papilloma formation. However, UVB radiation ...

Caging of the amidinium moieties of two representative bisbenzamidine DNA binders with suitable photoresponsive protecting groups suppresses their DNA-binding, which can then be fully recovered upon irradiation with UV light that removes the caging groups, regenerating the parent compounds. Moreover, a caged aza-pentamidine (©1a) is inert against Candida albicans, but displays a potent growth i...

The purpose of the present study was to evaluate how ultraviolet light <UV) irradiation using an ordinary UV sterilizer would affect the bonding of experimental composite resins to an autopolymerizing acrylic resin. To this end, three composite resins and one unfi11ed resin-of which the compositions were similar to commercial composite resin artifieial teeth were prepared as repair composites. ...

UV light provoked stress can evoke antioxidant defence system and consequently induces the synthesis of several phytochemical compounds. Th e aim of the present study was to investigate the infl uence of UV-B light irradiation on surface colour and synthesis of some bioactive compounds in apples skin of cultivars ‘Elstar’ and ‘Jonagold’. Half of each apple was shaded with aluminium foil to comp...

Akt/PKB plays a pivotal role in cell survival and proliferation. Previously, we reported that UV-irradiation induces extensive cell death in Akt2(-/-) mouse embryonic fibroblasts (MEFs) while Akt1(-/-) MEFs show cell cycle arrest. Here, we find that Akt1(-/-) MEFs exhibit phenotypic changes characteristics of senescence upon UV-irradiation. An enlarged and flattened morphology, a reduced cell p...

In order to study Staphylococcus epidermis and Staphylococcus aureus in vitro viability after the exposure to ultraviolet (UV) light and riboflavin, twelve strains of Staphylococcus epidermis and twelve strains of Staphylococcus aureus were isolated from patients with bacterial keratitis. The growth situation of Staphylococcus epidermidis and Staphylococcus aureus under different experimental c...

Octahedral anatase particles (OAPs) were prepared by hydrothermal (HT) reaction of titanate nanowires (TNWs). OAPs were modified with noble metals (Au, Ag, Cu and Pt) by two photodeposition methods: in the absence and in the initial presence of oxygen in the system. Photocatalytic activities for oxidative decomposition of acetic acid and anaerobic dehydrogenation of methanol under UV/vis irradi...

Here we present a method to produce TiO2 nanocrystals coated by thin layer of graphitic carbon. The coating process was prepared via chemical vapor deposition (CVD) with acetylene used as a carbon feedstock with TiO2 used as a substrate. Different temperatures (400°C and 500°C) and times (10, 20, and 60 s) of reaction were explored. The prepared nanocomposites were investigated by means of tran...

Abstract:  The optimum dose of UV irradiation to produce gynogenesis rainbow trout, Oncorhynchus mykiss with emphasis of Hertwing effect and photoreactivation (PR) was investigated. For this purpose, the sperm of rainbow trout were inadiated with UV at 2010±200 µw.cm-2 intensity in different alternatives of 0, 1, 3, 5, 8, 10, 15, 20, 25, 35 and 45 minutes and allowed to fertilize normal ova; th...

clavulanic acid is produced industrially by fermentation of streptomyces clavuligerus and researches have increased its production by strain improvement, recombinant dna technology, and media composition and growth condition optimization. the main objective of this study was to increase the level of clavulanic acid production from streptomyces clavuligerus (dsm 738), using uv irradiation. after...