PURPOSE To determine whether the severity of postprocedure pain associated with uterine artery embolization (UAE) for leiomyomata can be predicted and if its severity can predict outcome. MATERIALS AND METHODS Eighty-one patients underwent UAE and had postprocedure pain managed with use of patient-controlled analgesia (PCA) in the form of an intravenous morphine pump. Baseline uterine and dom...

One of the main causes of failure in uterine fibroid embolization procedures is incomplete infarction of the fibroid due to alternate vascular supply to the fibroid which was not identified by the operator. Cone-beam computed tomography angiography was used in this case to avoid nontarget embolization via a uterine artery, as well as identify incomplete embolization of the fibroid. This prompte...

BACKGROUND & OBJECTIVE Uterine fibroid embolization is an effective treatment alternative for uterine fibroids. However, amenorrhea after uterine fibroid embolization occurs in some patients. This study was to investigate the causes of amenorrhea after uterine fibroid embolization. METHODS Bilateral transcatheter uterine artery embolization was performed in 487 patients with uterine fibroids....

mediator complex subunit 12 (med12) is a part of the mediator complex, which is believed to regulate transcription. med12 is mutated at high frequency and with different mutation frequencies in uterine fibroids and breast fibroadenomas of different populations. this study aimed to analyze med12 mutations in senegalese population. med12 was sequenced in the tumoral tissues and blood samples of s...

STUDY QUESTION Can biologically active vitamin D3 [1,25(OH)₂D3] regulate the expression and activity of matrix metalloproteinases (MMPs) in human uterine fibroid cells? SUMMARY ANSWER 1,25(OH)₂D3 effectively reduced the expression and activities of MMP-2 and MMP-9 in cultured human uterine fibroid cells. WHAT IS KNOWN ALREADY Uterine fibroids (leiomyoma) express higher levels of MMP activit...

OBJECTIVE To estimate the prevalence of anemia, pelvic pain and heavy vaginal bleeding among symptomatic women with and without submucosal fibroids who presented for uterine fibroid embolization (UFE), and to determine if uterine weight was related to patient reports of heavy bleeding and pelvic pain. STUDY DESIGN A case series study was performed that reviewed the ambulatory medical records ...

OBJECTIVE To evaluate the use of serum prolactin and total protein as a tumor marker in diagnosing uterine fibroid(s). METHODS A case control study was carried out from March 2004 to October 2005 at Al-Kharch Hospital in Baghdad, Iraq. Thirty-two patients with uterine fibroid(s) and 30 healthy normal women were involved in the study. Blood was collected from uterine fibroid patients before an...

BACKGROUND There is no consensus as to whether uterine fibroids have any adverse effects on the outcomes of assisted reproduction treatment. This prospective study compared implantation/pregnancy rates of women with and without fibroids undergoing IVF-embryo transfer and measured uterine blood flow indices of the fibroid group. METHODS Patients who had fibroids that, during transvaginal scann...

Reprint requests to: Dr. Chi-Ming Lee Department of Diagnostic Radiology, Taipei Medical University Hospital. No. 252, Wu Hsing Street, Taipei 110, Taiwan, R.O.C. Uterine leiomyomas (f ibroids) are the most common benign neoplasm in women of childbearing age. Magnetic resonance-guided focused ultrasound ablation (MRgFUS) has been used worldwide to treat symptomatic uterine fibroids over the pas...

Uterine artery embolization (UAE) is an established, organ-preserving, safe and effective procedure in the therapeutic spectrum treatment of fibroid-related symptoms. The aim of UAE is the reduction or elimination of fibroid-related symptoms, but not the removal of the myoma. However, it also accomplishes a reduction of the size of the fibroid. There is a consensus between the disciplines of gy...