نتایج جستجو برای: usnic acid

تعداد نتایج: 747448  

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2006
Demet Cansaran Demet Cetin M Gökhan Halici Orhan Atakol

Three species of lichens, Rhizoplaca chrysoleuca (Sm.) Zopf, Rhizoplaca melanopthalma (DC.) Leuckert & Poelt and Rhizoplaca peltata Ramonds Leuckert, were collected from middle Anatolia, Erciyes Mountain (Kayseri) in Turkey. Their usnic acid amounts were determined by HPLC in acetone extracts. In addition, antimicrobial activities of these extracts were determined against Escherichia coli (ATCC...

Journal: :Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1997
A Fournet M E Ferreira A Rojas de Arias S Torres de Ortiz A Inchausti G Yaluff W Quilhot E Fernandez M E Hidalgo

Three secondary metabolites isolated from Chilean lichens, (+) usnic acid, pannarine and 1'-chloropannarine, were tested against promastigotes forms of three strains of Leishmania ssp. Pannarine and 1'-chloropannarine exhibited in vitro activity at 50 micrograms/ml and (+) usnic acid at 25 micrograms/ml. BALB/c mice infected with Leishmania amazonensis were treated 4 weeks post-infection with (...

Journal: :Brazilian journal of biology = Revista brasleira de biologia 2010
M A O'Neill M Mayer K E Murray H M L Rolim-Santos N S Santos-Magalhães A M Thompson V C L Appleyard

Usnic acid, a lichen metabolite, is known to exert antimitotic and antiproliferative activities against normal and malignant human cells. Many chemotherapy agents exert their activities by blocking cell cycle progression, inducing cell death through apoptosis. Microtubules, protein structure involved in the segregation of chromosomes during mitosis, serve as chemotherapeutical targets due to th...

Journal: :Molecules 2017
Béatrice Legouin Françoise Lohézic-Le Dévéhat Solenn Ferron Isabelle Rouaud Pierre Le Pogam Laurence Cornevin Michel Bertrand Joël Boustie

The extreme resiliency of lichens to UV radiations makes them an interesting model to find new photoprotective agents acting as UV-blockers and antioxidant. In this research, using a new in vitro method designed to overcome the shortage of material associated to many studies dealing with natural products, we show that the three major compounds isolated from the lichen Vulpicida pinastri, vulpin...

2015
João S. B. da Luz Erwelly B. de Oliveira Monica C. B. Martins Nicácio H. da Silva Luiz C. Alves Fábio A. B. dos Santos Luiz L. S. da Silva Eliete C. Silva Paloma L. de Medeiros

Leishmaniasis is considered by the World Health Organization as one of the infectious parasitic diseases endemic of great relevance and a global public health problem. Pentavalent antimonials used for treatment of this disease are limited and new phytochemicals emerge as an alternative to existing treatments, due to the low toxicity and cost reduction. Usnic acid is uniquely found in lichens an...

Journal: :Scientific American 1876

Journal: :Chemical and Pharmaceutical Bulletin 1980

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2007
Alejandra T Fazio Mónica T Adler María D Bertoni Claudia S Sepúlveda Elsa B Damonte Marta S Maier

Lichens and spore-derived cultured mycobionts of Teloschistes chrysophthalmus and Ramalina celastri were studied chemically, and results indicated that they produced, respectively, parietin and usnic acid as major secondary metabolites, which were purified and identified. Identification of the compounds was performed by high performance liquid chromatography and structural elucidation by nuclea...

Journal: :The Tokai journal of experimental and clinical medicine 1994
E C Periera S C Nascimento R C Lima N H Silva A F Oliveira E Bandeira M Boitard H Beriel C Vicente M E Legaz

Different fractions, isolated from the lichen Usnea fasciata, were analyzed by PC, TLC, and RP-HPLC. Analysis of the organic phases, mainly containing phenolics, revealed that usnic acid is the main product from secondary metabolites, whereas the polysaccharides isolichenin and raffinose are the most abundant water-soluble carbohydrates. Fractions containing usnic acid, as well as those contain...

Journal: :Chemical and Pharmaceutical Bulletin 1978

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