Acute kidney injury (AKI) induces adaptive responses within proximal tubular (PT) cells that serve to protect them from further ischemic or toxic damage. However, it is not known whether uremia, a potential consequence of AKI, independently alters susceptibility to tubular injury. To address this issue, we subjected CD-1 mice to bilateral ureteral transection (BUTx), which produces uremia (bloo...

the effect of orem self-care program performance on the self- care ability in elderly     hashemlo l [1] , hemmati maslakpak m [2] *, khalkhali h [3]     received: 3 dec , 2012 accepted: 12 feb , 2013     abstract:   background & aims : increase in the rate of elderly population in developing countries can cause emotional, social and health problems. using nursing theories especially orem theor...

In patients with renal insufficiency, the elevated plasma nonprotein nitrogen cannot be accounted for solely by the rise in the urea nitrogen (2). It is known that other nitrogenous materials such as creatinine and uric acid contribute to this elevation. Since free amino acids also contribute to the nonprotein, nonurea nitrogen of plasma, several investigators have determined the amino acid com...

Previous studies have suggested that an alteration in the expression of the NaK-ATPase of muscle may be an important determinant ofenhanced insulin sensitivity in chronic renal failure. Therefore, in the present studies we have examined the effect of uremia on the NaK-ATPase a isoforms in skeletal muscle, at the level of mRNA expression and enzymatic activity. The activity of the sodium pump, a...