Received for publication 8 February 1973 and in revised form 18 April 1973. measured with 3H20. Then MIRUS is calculated as: ([mg urea N excreted between 8 and 24 h after dose E] + [BUN at 24 h-BUN at 8 h] X [body water]) X (100/% recovery ["C]urea) X (1/kg BW314) X (1/ 16h). MRUS in 10 normal subjects averaged 65 mg urea N/h per kg BW"' (range 55-76), and in 34 cirrhotics 27 mg urea N/h per kg...

Urea Nitrogen to Creatinine Ratio Related Information: Creatinine, Serum or Plasma Osmolality, Serum Urea Nitrogen, Serum or Plasma Synonyms: BUN to Creatinine Ratio Test includes: Serum creatinine and serum urea nitrogen. Background: Useful to distinguish between preand postrenal diseases, gastrointestinal bleeding, and renal diseases. High BUN/creatinine ratio: Decreased renal perfusion, hypo...

Urea is the principal nitrogenous waste product of metabolism and is generated from protein breakdown. It is eliminated from the body almost exclusively by the kidneys in urine, and measurement of its concentration, first in urine and later in blood, has had clinical application in the assessment of kidney (renal) function for well over 150 years. This is the first of two articles that together...

in order to investigate the effect of diets contained urea and molasses on fattening performance and blood urea nitrogen (bun) density of male lambs, 72 arabic male lambs were used in a completely randomized design with a 3×4 factorial experiment, for 90 days. the experimental diets contained; 0, 0.5, 1 and 1.5% of urea each with 0, 7.5 and 15% of molasses, in isoprotein and isocalaric diets. t...

BACKGROUND Elevated blood urea nitrogen (BUN) observed in patients hospitalized for acute heart failure syndrome (AHFS) may represent increased neurohumoral activation. The purpose of this study was to examine the prognostic impact of BUN changes during hospitalization on the long-term prognosis of AHFS patients. METHODS AND RESULTS The Tohoku Acute Heart Failure Registry (n=497) is a multice...

AIMS The association between kinetics of blood urea nitrogen (BUN) levels in hospital and cardiovascular outcomes in patients with acutely decompensated congestive heart failure (HF) is unclear. We aimed to estimate the impact of changes in BUN level during hospitalization on clinical prognosis in patients with acute HF. METHODS AND RESULTS A total of 353 consecutive patients that were urgent...

At the 3rd Annual Ruminant Nutrition Symposium (Hammond, 1992), I reviewed the use of blood urea nitrogen (BUN) concentration for monitoring protein status in beef cattle, and discussed the potential for using milk urea nitrogen (MUN) as a noninvasive tool for monitoring protein status in dairy cattle. The purpose of this discussion is to review the basic concepts involved in urea nitrogen as a...

Klein and colleagues1 have retrospectively analyzed results derived from the prospective, randomized Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study and contribute an interesting article to this inaugural issue of Circulation: Heart Failure. Their analysis provides further evidence that the level of renal function in patient...

BACKGROUND Cisplatin (cis-diamminedichloroplatinum II; CP) is used widely as an antitumor drug in clinics, but is accompanied with renal toxicity. Cisplatin induced nephrotoxicity consists of change in kidney weight, histological changes in kidney and increase in serum creatinine (Cr) and blood urea nitrogen (BUN). This study was designed to find out a model for prediction of cisplatin induced ...

BACKGROUND Simple tools for risk stratification of patients with acute heart failure (AHF) are an unmet clinical need, particularly regarding long-term mortality. METHODS We prospectively enrolled 610 consecutive patients presenting to the emergency department with AHF. The diagnosis of AHF was adjudicated by two independent cardiologists. The classification and regression tree (CART) analysi...