Subunit influenza vaccines have the advantage of purity and a broad dosage range. Clinical studies were done with a new subunit vaccine produced by detergent fractionation with tri-(n-butyl) phosphate (TNBP). Acceptability by the recipients was compared in volunteers given 400 CCA units of A2 and 300 of B Influenza vaccine as either Sharples, zonal centrifuged, ether subunit, or TNBP subunit bi...

Subunit influenza vaccines have the advantage of purity and a broad dosage range. Clinical studies were done with a new subunit vaccine produced by detergent fractionation with tri-(n-butyl) phosphate (TNBP). Acceptability by the recipients was compared in volunteers given 400 CCA units of A2 and 300 of B Influenza vaccine as either Sharples, zonal centrifuged, ether subunit, or TNBP subunit bi...

Abstract Background and Aims: For more than half a century, the production of fowl pox vaccine at Razi Vaccine and Serum Research Institute, has been carried out by injection method in the chick chorioallantoic membrane (CAM) and the vaccine has a favorable and effective in poultry flocks and has provided a complete satisfaction to the poultry flocks owner. Fowl pox vaccine is also manufactured...

The Australian Paediatric Surveillance Unit (APSU) conducts national active surveillance of rare diseases of childhood, including infectious and vaccine preventable diseases, genetic disorders, childhood injuries and mental health conditions. The study of communicable and vaccine-preventable diseases is supported by the Australian Government Department of Health and Ageing through its communica...

The Australian Paediatric Surveillance Unit (APSU) conducts national active surveillance of rare diseases of childhood, including infectious and vaccine preventable diseases, genetic disorders, childhood injuries and mental health conditions. Studies of communicable and vaccine-preventable diseases are supported by the Australian Government Department of Health and Ageing through its communicab...

the plaque forming unit (pfu) and tissue culture infectious dose50 (tcid 50 ) methods are used for evaluation of vaccine heat stability and effect of various stabilizers on thermal stability of vaccines. the aim of present study is using real-time pcrtechniquefor estimation of vaccine degradation rate and thermal stability of measles vaccines. lyophilized measles vaccines containing three vario...

Shabir A Madhi, University of the Witwatersrand/Medical Research Council: Respiratory and Meningeal Pathogens Research Unit; and Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases; University of the Witwatersrand. Correspondence to: Shabir A Madhi, Old Potch Road, Chris Hani-Baragwanath Hospital, Respiratory and Meningeal Pathogens Research Unit, New...

Clostridium difficile is a leading cause of severe nosocomial infections. Cell-surface carbohydrate antigens are promising vaccine candidates. Here we report the first total synthesis of oligomers of the lipoteichoic acid antigen repeating unit. Synthetic glycan microarrays revealed anti-glycan antibodies in the blood of patients that help to define epitopes for vaccine development.

Domestic poultry serve as intermediates for transmission of influenza A virus from the wild aquatic bird reservoir to humans, resulting in influenza outbreaks in poultry and potential epidemics/pandemics among human beings. To combat emerging avian influenza virus, an inexpensive, heat-stable, and orally administered influenza vaccine would be useful to vaccinate large commercial poultry flocks...

Yersinia pestis is the etiological agent of bubonic and pneumonic plague, diseases which have caused over 200 milllion human deaths in the past. Plague still occurs throughout the world today, though for reasons that are not fully understood pandemics of disease do not develop from these outbreaks. Antibiotic treatment of bubonic plague is usually effective, but pneumonic plague is difficult to...