IMPORTANCE The standard recommended dose (0.1 U/kg per hour) of insulin in diabetic ketoacidosis (DKA) guidelines is not backed by strong clinical evidence. Physiologic dose-effect studies have found that even lower doses could adequately normalize ketonemia and acidosis. Lowering the insulin dose may be advantageous in the initial hours of therapy when a gradual decrease in glucose, electrolyt...

This experiment was conducted to investigate the effect of phytase superdoses alone or in combination with citric acid (CA) in canola meal-based diets severely limited in available phosphorus (Pa) on growth performance, plasma phosphorus (P), and tibia ash (TA) in broilers from 22 to 42 d of age. Two hundreds and eighty 21-d-old male broilers were used in 28 pens of 10 birds per each. The exper...

BACKGROUND Since only a portion of anemic patients outside the uremia setting benefit from erythropoietin treatment, a reliable means of predicting potential responders and nonresponders would be very useful. MATERIALS AND METHODS We retrospectively reviewed the clinical records of 58 patients with refractory anemia associated with various malignant disorders who had been treated with subcuta...

BACKGROUND Current guidelines for anticoagulation during left-sided procedures recommend the administration of unfractionated heparin (UFH) with an initial bolus of 50-100 U/kg, followed by continuous infusion to maintain an activated clotting time (ACT) ≥ 300 s. Our objective was to compare the effectiveness of this standard regimen (100 U/kg bolus) to a more aggressive approach (200 U/kg bolu...

this experiment was conducted to investigate the effect of phytase superdoses alone or in combination with citric acid (ca) in canola meal-based diets severely limited in available phosphorus (pa) on growth performance, plasma phosphorus (p), and tibia ash (ta) in broilers from 22 to 42 d of age. two hundreds and eighty 21-d-old male broilers were used in 28 pens of 10 birds per each. the exper...

retrospective and comparative study on the frequency of various types of leukemia in the past and in recent years, one can clearly note a sharp decline in ALL from over SOvv i-4 to so low an incidence as to doubt its occurrence in the middle and older age groups.58 If one accepts the author’s notion that ALL does not occur in elderly patients, this apparent fall in the reported incidence can be...

This retrospective chart review examines the safety of high-dose (> or = 15 U/kg body weight or > or = 800 total units) botulinum toxin type A (BOTOX, Allergan Inc., Irvine, CA) in children and young adults with spasticity. Ninety-four children weighing < 45 kg received a mean total dose of 334.1 U or 19.1 U/kg. Fourteen young adults weighing > or = 45 kg received a mean total dose of 927.3 U o...

BACKGROUND The incidence of diverticular disease of the colon has been rising in recent years, and the associated factors are: low ingestion of fibre, age, lack of physical activity, and obesity. METHODS A retrospective, descriptive, observational study was conducted on patients with the diagnosis of complicated diverticular disease requiring surgical or interventional treatment, for a period...

Background To attain whether the effects of low and high doses of estrogen progesterone luteinizing hormone (LH) and follicle stimulating hormone (FSH) in acute and chronic administration were related to oxidant and antioxidant parameters in rat uterine tissue as well as cyclooxygenase-1 (COX-1) activity. MaterialsAndMethods Acute and chronic administration of estrogen (1 and 5 mg/ kg) progeste...