In this paper, we considered the half logistic model and derived a probability density function that generalized it. The cumulative distribution function, the $n^{th}$ moment, the median, the mode and the 100$k$-percentage points of the generalized distribution were established. Estimation of the parameters of the distribution through maximum likelihood method was accomplished with the aid of c...

objective: serum leptin concentration reflects the body fat mass. there is controversial reports about the insulin effect on serum leptin concentration. we wanted to examine the effect of insulin therapy on serum leptin in children with new onset type i diabetes. materials and methods: this was a cross-sectional study in children's medical center on 34 children who had new onset type i dia...

Apatite minerals of I-type Zouzan granitoids and typical garnet-bearing S-type granites have been analyzed by electron microprobe to define trace element concentrations and compare them in different granites. Zouzan granites are composed of apatites with lower Fe, Mn, Na and HREE and higher REE and ∑REE relative to S-type ones. Trace elements abundances of apatite often vary with some parameter...

Background: Pancreatic islet transplantation is one of the most promising strategies for treating patients with type I diabetes mellitus.Objective: We aimed to assess the immunoisolation properties of the multilayer encapsulated islets using alginate-chitosan-PEG for immunoprotection and insulin secretion from the encapsulated islets induced under differe...

Background: Neurofibromatosis 1 (NF1) is a relatively common autosomal dominant condition. Among the complications of the disease, such as neurological disorders, hypertension and skeletal deformities, malignancy is the most serious one and is the main cause of early death in these patients. Objective: Review of cases of NF-1 associated with malignancies. Patents and Methods: In a retrospective...

defects in genes for survival motor neuron (smn) and neural apoptosis inhibitory proteins (naip) have been reported associated with spinal muscular atrophy (sma). among the genetic defects, deletions in exons 7 and 8 of smn and exons 4 and 5 of naip were found to be most significant. in the current study, 35 unrelated sma patients including 9 patients with type i, 6 with type ii, 20 with type i...

background because il2ra is considered a predisposing factor in the incidence of both type i diabetes and multiple sclerosis (ms), and considering that both are autoimmune diseases, some studies suggest a correlation between type i diabetes and ms. objectives the aim of this study was to examine the prevalence of type i diabetes among people with ms. patients and methods the study subjects comp...

background: type-i diabetes is an autoimmune inflammatory disease in which pancreatic ß-cells are selectively destroyed by infiltrating cells. tnf-related apoptosis-inducing ligand (trail) is a type-ii membrane protein of the tnf superfamily which is expressed in different tissues, including pancreas and lymphocytes. in humans, trail interacts with four membrane receptors. trail-r1 and trail-r2...