Diabetes mellitus is a group of heterogeneous metabolic disorders. A large number of pharmacological agents and animal models are used in study of diabetes for understanding the pathogenesis, complications, genetic and environmental influences. Animal models for type 1 diabetes range from animals with spontaneously developing autoimmune diabetic to chemical ablation of the pancreatic beta cells...

1Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IR Iran 2Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, IR Iran 3Department of Community Medicine, Alborz University of Medical Sciences, Karaj, IR Iran 4Non Com...

apoptosis is a complex network of biochemical and molecular pathway with fine regulatory mechanisms that control the death event during several pathological situations in multi cellular organisms. it is the part of normal development that occurs in a variety of diseases and is known as aberrant apoptosis. pancreatic β cell apoptosis is also a pathological feature which is common in both type 1 ...

Apoptosis is a complex network of biochemical and molecular pathway with fine regulatory mechanisms that control the death event during several pathological situations in multi cellular organisms. It is the part of normal development that occurs in a variety of diseases and is known as aberrant apoptosis. Pancreatic β cell apoptosis is also a pathological feature which is common in both type 1 ...

Globally, it is estimated that around 422 million adults had diabetes in 2014. Diabetics then have a higher risk of developing other diseases, such as: stroke and heart attack. Circadian rhythm disorders as sleep are one the factors causing type 2 mellitus. This study isintended to increase knowledge basis for further research on effect circadian misalignment mellitus determine diabetes. litera...

Neta Erez,1,2,3 Morgan Truitt,1,2,3 Peter Olson,1,2,3 and Douglas Hanahan1,2,3,4,* 1Helen Diller Family Comprehensive Cancer Center 2Diabetes Center 3Department of Biochemistry and Biophysics University of California San Francisco, San Francisco, CA 94143, USA 4Present address: Swiss Institute for Experimental Cancer Research, Swiss Federal Institute of Technology Lausanne, Lausanne CH-1015, Sw...

Diabetes mellitus (DM) is a growing global problem where, increased oxygen free radicals are responsible for the complications. Clinical evidence of Eugenia jambolana seeds for use in DM is lacking. This is an open labeled, randomized trial in DM patients: fifteen in group1 received Eugenia Jambolana seed powder 10 gm orally per day along with diet and exercise, and ten in group 2 on diet and e...