Radiation oncology is a medical discipline mainly involved in the treatment of cancer with ionizing radiation. It is based on full knowledge of individual patient cancer disease, delineation of the target volume including tumor that has to receive therapeutic radiation dose, delineation of normal tissues to be spared, treatment planning with dedicated calculation algorithms, radiation delivery ...

The improved accuracy in tumor identification with FDG-PET has led to its increased utilization in target volume delineation for radiotherapy treatment planning in the treatment of lung cancer. However, PET/CT has constantly been influenced by respiratory motion-related image degradation, which is especially prominent for small lung tumors in the peri-diaphragmatic regions of the thorax. Here, ...

Background: The dynamic phantom is one of the best tools to study the impact of motion on tumor target delineation and absorbed dose verification during dose delivery. Materials and Methods: this study, a 6-DOF (degrees of freedom) phantom was designed following the stacked serial kinematics and assembled by six commercial motion stages to generate 6-DOF motion, which were RotX (pitch, around X...

Fluorine-18-fluorodeoxyglucose- positron emission tomography ((18)F-FDG PET) in head and neck cancer patients is useful for staging, identification of macroscopic disease, detection of invaded lymph nodes and distant metastases, delineation of radiotherapy target volume and assessment of treatment response. This brief review addresses the potential role of PET in radiotherapy planning as compar...

OBJECTIVE To evaluate a semi-automated PET-image tumor segmentation algorithm for gross tumor volume (GTV) delineation in patients with locally advanced cervical cancer. MATERIAL AND METHODS Thirty-two patients with locally advanced cervical cancer were retrospectively evaluated. Semi-automated PET-image-based GTV delineation was applied using a previous established algorithm (GTV2SD) and 2 f...

Magnetic resonance imaging (MRI) is a crucial tool for clinical brain tumor detection and delineation. Since the process of gross tumor volume delineation resides with clinicians, a better understanding of how they perform this task is required if improvements in life expectancy are to be made. Novice-expert comparison studies have been used to examine the effect of expertise on abnormality det...

objective(s): considering the fact that the standardized uptake value (suv) of a normal lung tissue is expressed as x±sd, x+3×sd could be considered as the threshold value to outline the internal tumor volume (itv) of a lung neoplasm. methods: three hollow models were filled with 55.0 kbq/ml fluorine18- fluorodeoxyglucose (18f-fdg) to represent tumors. the models were fixed to a barrel filled w...

background: to determine which radiotherapy parameters are associated with the tumor response of locally advanced non-small cell lung cancer (nsclc) patients undergoing concurrent chemoradiotherapy. materials and methods: thirty one patients with iiia/iiib nsclc underwent chemoradiotherapy with a median dose of 63 gy. on our actual treatments, we made radiotherapy planning to cover the planning...