Background: In this study, the effects of three structural analogues of adenosine upon proliferation of human tumor cells were investigated. Previous research showed a cytotoxic effect of adenosine via A3 receptor and A1 receptor and sometimes this effect was receptor independent. The researches showed a differential cytotoxic effect of adenosine and its A3 agonists on cancerous cells, while ot...

Background: Due to abscopal effect, cell damage may occur outside of the radiation field and the quantification of this effect is one of the most challenging debates in radiation therapy. The aim of this study was to estimate the abscopal effect induced in non-irradiated tumors quantitatively by means of biological effective dose (BED). Materials and Methods: Breast tumors using 4T1 and MC4-L2 ...

background: genistein (gen), a naturally occurring flavonoid present in soy bean, has attracted scientific interest for its possible benefits in cancer. objective: the potential immunomodulatory effects of genistein on the immune system and against tc-1 tumor cell line were evaluated in adult female c57bl/6 mice. methods: mice were treated with gen 10 days before to 10 days after the tumor indu...

background: neuroblastoma is the most common tumor in infancy and wilms’ tumor is the most common malignant tumor of kidney in childhood. both the tumors are usually within the differential diagnosis of each other. this study compares the clinical manifestations, sex and age distribution of childhood wilms’ tumor and neuroblastoma at one of tehran children hospitals. materials and methods: the ...

abstract gastrointestinal mesenchymal tumors are a group of tumors originating from the mesenchymal stem cells of the gi tract. digestive tract schwannomas are rare mesenchymal tumors which occur most frequently in the stomach. we report a 56-yearold woman who was examined endoscopically for dyspepsia which she had suffered from since 3 years ago. around gastric antral mass was seen. surgical r...

In this study, 22 patients (15-75 years old) were selected and transferred to CT scan for tumor ablation. For ablations, after prep and drep under the local anesthesia and mild sedation in proper position, small incision made and special needle inserted and guided by proper direction to the core of the tumor. Then, laser probe inserted through the needle and laser energy delivered. Although we ...

Objective(s):Sea cucumber is one of the classes of echinoderms, which is considered as a health marine product and possess various biological characteristics with therapeutic application. The present investigation attempted to evaluate the potential of anti-cancer Persian Gulf sea cucumber species Holothuria arenicola (H. arenicola) aqueous extract on mice colon carcinoma cells in vitro and in ...

purpose: to present a case of orbital granular cell tumor, a rare orbital tumor. case report: a 55-year-old woman presented with binocular diplopia and right ocular displacement. the problem had initiated 3 years ago. a firm nontender mass at the region of the right lower lid was visible. orbital ct-scan disclosed a well-defined mass in the inferior right orbit with involvement of the inferior ...